Animal Cell Culture (eBook)

PrefaceChapter 1: Cell line developmentHansjoerg HauserChapter 2: Transient recombinant protein expression in mammalian cellsVolker Jäger, Konrad Büssow, Thomas SchirrmannChapter 3: Hybridoma technology for the in vitro production of therapeutic antibodiesSusan McDonnellChapter 4: Bioreactors for mammalian cells                                                 R. PörtnerChapter 5: Mass Transfer and Mixing Across the Scales in Animal Cell CultureAlvin W NienowChapter 6: Hydrodynamic Damage to Animal CellsJeffrey J Chalmers and Ningning MaChapter 7: Monitoring of cell cultureSebastian Schwamb, Robert Puskeiler, Philipp WiedemannChapter 8: Serum and protein free media Michael ButlerChapter 9: Glycosylation in Cell CultureMaureen Spearman and Michael ButlerChapter 10: Modelling of mammalian cell cultures Nishikant P. Shirsat, Niall J. English, Brian Glennon and Mohamed Al-RubeaiChapter 11: Mammalian Cell Line Selection Strategies for High-ProducersDarrin Kuystermans and Mohamed Al-RubeaiChapter 12: Building a Cell Culture Process with Stable Foundations: Searching for Certainty in an Uncertain WorldPeter M O’Callaghan and Andrew J RacherChapter 13: Perfusion ProcessesVeronique ChotteauChapter 14 : Single-use bioreactors for animal and human cellsStephan C. Kaiser, Matthias Kraume, Dieter Eibl, and Regine EiblChapter 15 : An Overview of Cell Culture Engineering for the Insect Cell-Baculovirus Expression Vector System (BEVS)Laura A. Palomares, Mauricio Realpe and Octavio T. RamirezChapter 16 : Metabolic flux analysis: a powerful tool in animal cell cultureJoão V. Sá, Tiago M. Duarte, Manuel J. T. Carrondo, Paula M. Alves, Ana P. TeixeiraChapter 17 : Cell immobilization for the production of viral vaccinesAna Carina Silva, António Roldão, Ana Teixeira, Paulo Fernandes, Marcos F.Q. Sousa, Paula M. AlvesChapter 18 : Cell Engineering for Therapeutic Protein ProductionEric Baek, Che Lin Kim, Jin Hyoung Park, and Gyun Min LeeChapter 19 : Proteomics in Cell Culture: From genomics to combined ‘omics for cell line engineering and bioprocess developmentKelley Heffner, Christian Kaas, Amit Kumar, Deniz Baycin-Hizal, Michael BetenbaughChapter 20 : Metabolomics in animal cell cultureMiroslava Čuperlović-CulfChapter 21 : Process Analytical Technology and Quality-by-Design for Animal Cell Culture Stephen Craven and Jessica WhelanChapter 22 : Biosafety recommendations on the handling of animal cell cultures Philippe Herman and Katia PauwelsChapter 23 : Biopharmaceutical products from animal cell cultureDarrin Kuystermans and Mohamed Al-RubeaiIndex