The use of animal models is a key aspect of scientific research in numerous fields of medicine. Movement Disorders, Second Edition vigorously examines the important contributions and application of animal models to the understanding of human movement disorders, and serves as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration, and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. - Introduces the scientific foundations for modern movement disorders research- Contributing authors are internationally known experts- Completely revised with 20% new material- Provides a comprehensive discussion of genetics for each type of movement disorder- Covers Parkinson's disease, Huntington's disease, dystonia, tremors, and tics
Front Cover 1
Movement Disorders 4
Contributors
Rami R. Ajjuri, Department of Biology, University of Alabama, Tuscaloosa, AL, USA
Yousuf Ali
Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, FL, USA
The Cain Foundation Laboratories, Jan and Dan Duncan Neurology Institute, Baylor College of Medicine, Houston, TX, USA
Giuseppe Arena, Mendel Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
Tetsuo Ashizawa, Department of Neurology, College of Medicine, The McKnight Brain Institute, University of Florida, Gainesville, FL, USA
Georg Auburger, Experimental Neurology, Goethe University Medical School, Frankfurt am Main, Germany
Devika P. Bagchi, Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
Barbara Baldo, Translational Neuroendocrine Research Unit, Department of Experimental Medical Sciences, Lund University, Lund, Sweden
Sally L. Baxter, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
Robert F. Berman, Department of Neurological Surgery, University of California Davis, Davis, CA, USA
Lester I. Binder, Deceased
Craig Blackstone, Cell Biology Section, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
Carlo Breda, Department of Genetics, University of Leicester, Leicester, UK
Jonathan M. Brotchie, Toronto Western Research Institute, Toronto Western Hospital, ON, Canada
Edward A. Burton
Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, USA
Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA
Geriatric Research Education and Clinical Center, Pittsburgh VA Healthcare System, Pittsburgh, PA, USA
Department of Neurology, Pittsburgh VA Healthcare System, Pittsburgh, PA, USA
Diany Paola Calderon, Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY, USA
Guy A. Caldwell, Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, USA
Kim A. Caldwell, Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, USA
M. Angela Cenci, Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden
Jianmin Chen, Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA
Marie-Francoise Chesselet, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Lyndsey E. Collins-Praino, Department of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, Adelaide, Australia
Carlo Colosimo, Department of Neurology and Psychiatry, Sapienza University, Rome, Italy
Benjamin Combs, Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA
Mercè Correa
Department of Psychology, University of Connecticut, Storrs, CT, USA
Area of Psychobiology, University Jaume I, Castelló, Spain
Maria Cristina D’Adamo
Department of Experimental Medicine, Section of Physiology and Biochemistry, University of Perugia, Perugia, Italy
Euro-Mediterranean Institute of Science and Technology, IEMEST, Palermo, Italy
Helena Dai, Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, USA
Debkanya Datta, Molecular Neurobiology Laboratory, Department of Psychiatry and Program in Neuroscience, Harvard Stem Cell Institute, Belmont, MA, USA
Mark P. DeAndrade, Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, USA
Paula Dietrich, Department of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA
Ioannis Dragatsis, Department of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA
David Eidelberg, Center for Neurosciences, The Feinstein Institute for Medical Research, Manhasset, NY, USA
Sherif F. El-Khamisy
Krebs Institute, University of Sheffield, Sheffield, UK
Center for Genomics, Zewail City of Science and Technology, Giza, Egypt
Craig L. Evinger, Departments of Neurobiology & Behavior and Ophthalmology, SUNY Stony Brook, Stony Brook, NY, USA
Coralie Fassier, UMR CNRS 7224, Inserm U952, University Pierre and Marie CURIE, Paris, France
Maciej Figiel, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego, Poznan, Poland
Susan H. Fox
Division of Neurology, University of Toronto, ON, Canada
Toronto Western Research Institute, Toronto Western Hospital, ON, Canada
Veronica Francardo, Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden
Amanda A.H. Freeman, Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA
Steven Frucht, Robert and John M. Bendheim Parkinson and Movement Disorders Center, Mount Sinai School of Medicine, New York, NY, USA
John Gardiner, The School of Biological Sciences, The University of Sydney, NSW, Australia
Benoit Giasson, Center for Translational Research of Neurodegenerative Disease and Department of Neuroscience, University of Florida, Gainesville, FL, USA
Flaviano Giorgini, Department of Genetics, University of Leicester, Leicester, UK
Suzana Gispert, Experimental Neurology, Goethe University Medical School, Frankfurt am Main, Germany
Pilar González-Cabo
Program in Rare and Genetic Diseases, Príncipe Felipe Research Center, Valencia, Spain
IBV/CSIC Associated Unit, Príncipe Felipe Research Center, Valencia, Spain
CIBER of Rare Illnesses, Valencia, Spain
Viviana Gradinaru, Division of Biology, California Institute of Technology, California Boulevard, Pasadena, CA, USA
Marleshia Hall, Department of Biology, University of Alabama, Tuscaloosa, AL, USA
Hiroko Hama, Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA
Adrian Handforth, Neurology Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA
Susan Hayflick, Departments of Molecular and Medical Genetics, Pediatrics and Neurology, Oregon Health and Science University, Portland, OR, USA
Jamilé Hazan, UMR CNRS 7224, Inserm U952, University Pierre and Marie CURIE, Paris, France
Peter Hedera, Department of Neurology and Center for Molecular Neuroscience, Vanderbilt University, Nashville, TN, USA
Gary A. Heiman, Human Genetics Institute of New Jersey and Department of Genetics, Rutgers University, Piscataway, NJ, USA
Karl Herrup
Division of Life Science, Hong Kong University of Science and Technology, Kowloon, Hong Kong
Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA
Ellen J. Hess
Department of Pharmacology, Emory University School of Medicine, Atlanta, GA, USA
Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA
Patrick Hickey, Department of Neurology, Duke University Medical Center, Durham, NC, USA
Diana S. Himmelstein, Department of Cell and Molecular Biology, Fienberg School of Medicine, Northwestern University, Chicago, IL, USA
Pieter...
Erscheint lt. Verlag | 24.10.2014 |
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Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie |
Naturwissenschaften ► Biologie ► Humanbiologie | |
Naturwissenschaften ► Biologie ► Zoologie | |
ISBN-10 | 0-12-405516-8 / 0124055168 |
ISBN-13 | 978-0-12-405516-2 / 9780124055162 |
Haben Sie eine Frage zum Produkt? |
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Größe: 49,5 MB
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eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
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