Movement Disorders -

Movement Disorders (eBook)

Genetics and Models

Mark S. LeDoux (Herausgeber)

eBook Download: PDF | EPUB
2014 | 2. Auflage
1258 Seiten
Elsevier Science (Verlag)
978-0-12-405516-2 (ISBN)
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The use of animal models is a key aspect of scientific research in numerous fields of medicine. Movement Disorders, Second Edition vigorously examines the important contributions and application of animal models to the understanding of human movement disorders, and serves as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration, and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. - Introduces the scientific foundations for modern movement disorders research - Contributing authors are internationally known experts - Completely revised with 20% new material - Provides a comprehensive discussion of genetics for each type of movement disorder - Covers Parkinson's disease, Huntington's disease, dystonia, tremors, and tics
The use of animal models is a key aspect of scientific research in numerous fields of medicine. Movement Disorders, Second Edition vigorously examines the important contributions and application of animal models to the understanding of human movement disorders, and serves as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration, and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. - Introduces the scientific foundations for modern movement disorders research- Contributing authors are internationally known experts- Completely revised with 20% new material- Provides a comprehensive discussion of genetics for each type of movement disorder- Covers Parkinson's disease, Huntington's disease, dystonia, tremors, and tics

Front Cover 1
Movement Disorders 4

Contributors


Rami R. Ajjuri,     Department of Biology, University of Alabama, Tuscaloosa, AL, USA

Yousuf Ali

Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, FL, USA

The Cain Foundation Laboratories, Jan and Dan Duncan Neurology Institute, Baylor College of Medicine, Houston, TX, USA

Giuseppe Arena,     Mendel Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy

Tetsuo Ashizawa,     Department of Neurology, College of Medicine, The McKnight Brain Institute, University of Florida, Gainesville, FL, USA

Georg Auburger,     Experimental Neurology, Goethe University Medical School, Frankfurt am Main, Germany

Devika P. Bagchi,     Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA

Barbara Baldo,     Translational Neuroendocrine Research Unit, Department of Experimental Medical Sciences, Lund University, Lund, Sweden

Sally L. Baxter,     Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Robert F. Berman,     Department of Neurological Surgery, University of California Davis, Davis, CA, USA

Lester I. Binder,     Deceased

Craig Blackstone,     Cell Biology Section, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA

Carlo Breda,     Department of Genetics, University of Leicester, Leicester, UK

Jonathan M. Brotchie,     Toronto Western Research Institute, Toronto Western Hospital, ON, Canada

Edward A. Burton

Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, USA

Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA

Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA

Geriatric Research Education and Clinical Center, Pittsburgh VA Healthcare System, Pittsburgh, PA, USA

Department of Neurology, Pittsburgh VA Healthcare System, Pittsburgh, PA, USA

Diany Paola Calderon,     Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, NY, USA

Guy A. Caldwell,     Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, USA

Kim A. Caldwell,     Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, USA

M. Angela Cenci,     Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden

Jianmin Chen,     Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA

Marie-Francoise Chesselet,     Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA

Lyndsey E. Collins-Praino,     Department of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, Adelaide, Australia

Carlo Colosimo,     Department of Neurology and Psychiatry, Sapienza University, Rome, Italy

Benjamin Combs,     Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA

Mercè Correa

Department of Psychology, University of Connecticut, Storrs, CT, USA

Area of Psychobiology, University Jaume I, Castelló, Spain

Maria Cristina D’Adamo

Department of Experimental Medicine, Section of Physiology and Biochemistry, University of Perugia, Perugia, Italy

Euro-Mediterranean Institute of Science and Technology, IEMEST, Palermo, Italy

Helena Dai,     Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, USA

Debkanya Datta,     Molecular Neurobiology Laboratory, Department of Psychiatry and Program in Neuroscience, Harvard Stem Cell Institute, Belmont, MA, USA

Mark P. DeAndrade,     Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, USA

Paula Dietrich,     Department of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA

Ioannis Dragatsis,     Department of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA

David Eidelberg,     Center for Neurosciences, The Feinstein Institute for Medical Research, Manhasset, NY, USA

Sherif F. El-Khamisy

Krebs Institute, University of Sheffield, Sheffield, UK

Center for Genomics, Zewail City of Science and Technology, Giza, Egypt

Craig L. Evinger,     Departments of Neurobiology & Behavior and Ophthalmology, SUNY Stony Brook, Stony Brook, NY, USA

Coralie Fassier,     UMR CNRS 7224, Inserm U952, University Pierre and Marie CURIE, Paris, France

Maciej Figiel,     Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego, Poznan, Poland

Susan H. Fox

Division of Neurology, University of Toronto, ON, Canada

Toronto Western Research Institute, Toronto Western Hospital, ON, Canada

Veronica Francardo,     Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden

Amanda A.H. Freeman,     Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA

Steven Frucht,     Robert and John M. Bendheim Parkinson and Movement Disorders Center, Mount Sinai School of Medicine, New York, NY, USA

John Gardiner,     The School of Biological Sciences, The University of Sydney, NSW, Australia

Benoit Giasson,     Center for Translational Research of Neurodegenerative Disease and Department of Neuroscience, University of Florida, Gainesville, FL, USA

Flaviano Giorgini,     Department of Genetics, University of Leicester, Leicester, UK

Suzana Gispert,     Experimental Neurology, Goethe University Medical School, Frankfurt am Main, Germany

Pilar González-Cabo

Program in Rare and Genetic Diseases, Príncipe Felipe Research Center, Valencia, Spain

IBV/CSIC Associated Unit, Príncipe Felipe Research Center, Valencia, Spain

CIBER of Rare Illnesses, Valencia, Spain

Viviana Gradinaru,     Division of Biology, California Institute of Technology, California Boulevard, Pasadena, CA, USA

Marleshia Hall,     Department of Biology, University of Alabama, Tuscaloosa, AL, USA

Hiroko Hama,     Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA

Adrian Handforth,     Neurology Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA

Susan Hayflick,     Departments of Molecular and Medical Genetics, Pediatrics and Neurology, Oregon Health and Science University, Portland, OR, USA

Jamilé Hazan,     UMR CNRS 7224, Inserm U952, University Pierre and Marie CURIE, Paris, France

Peter Hedera,     Department of Neurology and Center for Molecular Neuroscience, Vanderbilt University, Nashville, TN, USA

Gary A. Heiman,     Human Genetics Institute of New Jersey and Department of Genetics, Rutgers University, Piscataway, NJ, USA

Karl Herrup

Division of Life Science, Hong Kong University of Science and Technology, Kowloon, Hong Kong

Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA

Ellen J. Hess

Department of Pharmacology, Emory University School of Medicine, Atlanta, GA, USA

Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA

Patrick Hickey,     Department of Neurology, Duke University Medical Center, Durham, NC, USA

Diana S. Himmelstein,     Department of Cell and Molecular Biology, Fienberg School of Medicine, Northwestern University, Chicago, IL, USA

Pieter...

Erscheint lt. Verlag 24.10.2014
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
ISBN-10 0-12-405516-8 / 0124055168
ISBN-13 978-0-12-405516-2 / 9780124055162
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