Photoreceptors and Calcium
Springer-Verlag New York Inc.
978-1-4613-4933-4 (ISBN)
Similarly, mu- 2 tant genes encoding cation or Ca+ channels (cyclic nucleotide-gated cation chan- 2 nels located in the cell membrane and L-type voltage-gated Ca+ channels located at the synapse of photo receptors) lead to retinitis pigmentosa or congenital stationary night blindness. In phototransduction of invertebrate organisms (e. g. , Drosophila 2 and Limulus), the role of Ca+ is similarly central, but distinct, from that of vertebrates.
1. Calcium and Phototransduction.- 2. The Calcium Gradient Along the Rod Outer Segment.- 3. The Time Course of Light Adaptation in Vertebrate Retinal Rods.- 4. S-Modulin.- 5. Ca2+-Dependent Control of Rhodopsin Phosphorylation: Recoverin and Rhodopsin Kinase.- 6. Recoverin and Rhodopsin Kinase.- 7. Pathological Roles of Recoverin in Cancer-Associated Retinopathy.- 8. Rgs9-1 Phosphorylation and Ca2+.- 9. Phosphorylation by Cyclin-Dependent Protein Kinase 5 of the Regulatory Subunit (p?) of Retinal Cgmp phosphodiesterase (pde6): its Implications in Phototransduction.- 10. Centrins, Anovel Group of Ca2+-Binding Proteins in Vertebrate Photoreceptor Cells.- 11.Tuning Outer Segment Ca2+Homeostasis to Phototransduction in Rods and Cones.- 12. Regulation of the Rod Photoreceptor Cyclic Nucleotide-Gated Channel.- 13. Ca2+-Channels in the Rpe.- 14. THE RETINAL ROD AND CONE Na+/Ca2+-K+EXCHANGERS.- 15.THE COMPLEX OF cGMP-GATED CHANNELAND Na+/Ca2+-K+EXCHANGER IN ROD PHOTORECEPTORS.- 16. Regulation of Voltage-8Ensitive Ca2+Channels in Bipolar Cells by Divalent Cations and Polyamines.- 17. Site-Directed and Natural Mutations in Studying Functional Domains in Guanylyl Cyclase Activating Proteins (Gcaps).- 18. Calmodulin and Ca2+-Binding Proteins (Cabps): Variations on Atheme.- 19. GCAPs: Ca2+-SENSITIVE REGULATORS OF retGC.- 20. Structure and Membrane-Targeting Mechanism of Retinal Ca2+-Binding Proteins, Recoverin and Gcap-2.- 21. Target Recognition of Guanylate Cyclase by Guanylate Cyclase-Activating Proteins.- 22. Mouse Models to Study Gcap Functions in Intact Photoreceptors.- 23. Calcium-Dependent Activation of Guanylate Cyclase by S100b.- 24. The Role of Cadherins in Ca2+-Mediated Cell Adhesion and Inherited Photoreceptor Degeneration.- 25. Guanylate Cyclase Activating Proteins,Guanylate Cyclase and Disease.- 26. Using Mutant Mice to Study the Role of Voltage-Gated Calcium Channels in the Retina.- 27. Caldendrins in the Inner Retina.- 28. Calcium Channels at the Photoreceptor Synapse.- 29. On Bipolar Cells: Following in the Footsteps of Phototransduction.- 30. Ca2+Regulation of Drosophila Phototransduction.- 31. Simultaneous Roles for Ca2+in Excitation and Adaptation of Limulus Ventral Photoreceptors.- 32. Calcium Homeostasis in Fly Photoreceptor Cells.- 33. Photoreceptor Degeneration and Ca2+Influx Through Light-Activated Channels of Drosophila.- 34. The Trp Calcium Channeland Retinal Degeneration.
Reihe/Serie | Advances in Experimental Medicine and Biology ; 514 |
---|---|
Zusatzinfo | XXVIII, 625 p. |
Verlagsort | New York, NY |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie ► Ökologie / Naturschutz | |
Naturwissenschaften ► Physik / Astronomie ► Festkörperphysik | |
Weitere Fachgebiete ► Land- / Forstwirtschaft / Fischerei | |
ISBN-10 | 1-4613-4933-8 / 1461349338 |
ISBN-13 | 978-1-4613-4933-4 / 9781461349334 |
Zustand | Neuware |
Haben Sie eine Frage zum Produkt? |
aus dem Bereich