XIth International Symposium on Amyloidosis (eBook)

Featuring the work of pioneering investigators, including Nobel Laureate, Dr. Stanley Prusiner, this comprehensive volume begins with a study of the mechanisms of fibril formation and cellular response and discusses emerging diagnostic and translational approaches. It covers-Possible horizontal transmissionCharge differences of deposits in AL and NALCDDNovel assays to detect amyloid induced apoptosisAA and localized amyloidosisHereditary gelsolin amyloidosis, and other novel mutationsALBASE as a platform analysis toolAL amyloidosis in the elderlyNaturally occurring antibodies as a potential therapyClinical trials of melphalan-dexamethasoneAutologous stem cell transplantation

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Edited by a stellar team of scientists compiling more than 120 papers into a single tome, the XIth Annual International Symposium on Amyloidosis represents the most important review of the state-of-the-science and future directions of the field. An unparalleled cast of pioneering researchers, including keynote speaker and Nobel Laureate, Dr. Stanley Prusiner, present groundbreaking research in systemic amyloidosis including the mechanisms of disease and cellular toxicity, AA amyloidosis, familial amyloidosis, AL amyloidosis, clinical trials, and emerging translational approaches. Focusing on new basic and translational medicine approaches in systemic amyloidosis, this book provides clinicians and researchers with an invaluable reference to the most up-to-date research in the field.