Stem Cells and Human Diseases -

Stem Cells and Human Diseases (eBook)

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2012 | 2012
X, 630 Seiten
Springer Netherland (Verlag)
978-94-007-2801-1 (ISBN)
Systemvoraussetzungen
213,99 inkl. MwSt
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The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell self-renewal, tissue homeostasis and drug resistance are also mentioned. Overall, these reviews will provide a new understanding of the influence of stem cells in tissue regeneration, disease regulation, therapy and drug resistance in several human diseases.
The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell self-renewal, tissue homeostasis and drug resistance are also mentioned. Overall, these reviews will provide a new understanding of the influence of stem cells in tissue regeneration, disease regulation, therapy and drug resistance in several human diseases.

Cancer Stem Cells: Biology, Perspectives and Therapeutic Implications; Brahma N. Singh, Sharmila Shankar and Rakesh K. SrivastavaThe Perspectives of Stem Cell-based Therapy in Neurological Diseases; Wojciech Maksymowicz, Joanna Wojtkiewicz, Hanna Kozłowska, Aleksandra Habich and Wlodek LopaczynskiStem Cell-based Therapy for Lysosomal Storage Diseases; Brittni A. Scruggs, Xiujuan Zhang, Jeffrey M. Gimble and Bruce A. BunnellDrosophila germline stem cells; Yalan Xing and Willis X. LiMesenchymal Stem Cells in Hematopoietic Stem Cell Transplantation; Peiman Hematti, Jaehyup Kim and Minoo BattiwallaCancer Stem Cells in Solid Tumors, Markers and Therapy; Ortiz-Sánchez Elizabeth, González-Montoya José Luis, Langley Elizabeth and García-Carrancá AlejandroCancer Stem Cells: Paradigm Shifting or Perishing Concept?; Senthil K Pazhanisamy and Keith Syson Chan†Genomics of Prostate Cancer; Kern Rei Chng, Shin Chet Chuah, Edwin CheungIschemia, reactive radicals, redox signaling and hematopoietic stem cells; Suman Kanji, Vincent J. Pompili and Hiranmoy DasCancer stem cell models and role in drug discovery; Rohit Duggal, Boris Minev, Angelo Vescovi and Aladar SzalayOrigins of Metastasis-Initiating Cells; Sara M. Nolte and Sheila K. SinghThe Reduction of Callus Formation during Bone Regeneration by BMP-2 and Human Adipose Derived Stem Cells; Claudia Keibl and Martijn van GriensvenStem cells and leukemia; Vincenzo Giambra and Christopher R. JenkinsThe role of adult bone marrow derived mesenchymal stem cells, growth factors and scaffolds in the repair of cartilage and bone; Antal Salamon and Erzsébet ToldyWorth the Weight: Adipose Stem Cells in Human Disease; Saleh Heneidi and Gregorio ChazenbalkNeural crest and Hirschsprung’s disease; Kim Hei-Man CHOW , Paul Kwong-Hang TAM, Elly Sau-Wai NGANCommon denominators of self-renewal and malignancy IN neural stem cells and GLIOMA; Grzegorz Wicher, Karin Holmqvist and Karin Forsberg-NilssonStem-like cells from brain tumours or vice versa?; Sara G.M. PiccirilloTranslating Mammary Stem Cell and Cancer Stem Cell Biology to the Clinics; Rajneesh Pathania, Vadivel Ganapathy and Muthusamy ThangarajuBreast Cancer Stem Cells; Shane R. Stecklein and Roy A. Jensen Translin/TRAX deficiency affects mesenchymal differentiation programs and induces bone marrow failure; Reiko Ishida, Katsunori Aoki, Kazuhiko Nakahara, Yuko Fukuda, Momoko Ohhori, Yumi Saito, Kimihiko Kano, Junichiro Matsuda, Shigetaka Asano, Richard T. Maziarz and Masataka KasaiCancer therapies and Stem cells; Hiromichi KimuraCancer Stem Cells and Head and Neck Squamous Cell Carcinomas; Shi-Long LuThe Biology of Lung Cancer Stem Cells; Sandeep Singh and Srikumar P. ChellappanStem Cell Characters in Primary and Metastatic Tumour Establishment; Maria Tsekrekou, Dimitris Mavroudis, Dimitris Kafetzopoulos, Despoina VassouPlasticity of Cancer Stem Cells; Zhizhong LiCross talks among Notch, Wnt, and Hedgehog signaling pathways regulate stem cell characteristics; Su-Ni Tang, Sharmila Shankar, and Rakesh K. SrivastavaGlobal OMICs profiling and functional analysis of CD44+/CD24- stem-like cells in normal human breast tissue and breast cancer; Marina Bessarabova, Kornelia Polyak, Yuri NikolskyBreast Cancer Stem Cells: Isolation, characterization and targeting; Anurag N. Paranjape

Erscheint lt. Verlag 31.1.2012
Zusatzinfo X, 630 p.
Verlagsort Dordrecht
Sprache englisch
Themenwelt Geisteswissenschaften
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Sozialwissenschaften Pädagogik
Technik
Schlagworte Cancer Stem Cells • drug resistance • Entomology • microRNA • Physiology and Metabolisms • Stem Cells
ISBN-10 94-007-2801-8 / 9400728018
ISBN-13 978-94-007-2801-1 / 9789400728011
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