International Review of Cytology (eBook)

Cover Page 1
Contents 6
Contributors 10
Chapter 1: Endogenous Ligands of PACAP/VIP Receptors in the Autocrine-Paracrine Regulation of the Adrenal Gland 12
I. Introduction 13
II. Biology of PACAP/VIP Receptors and Their Endogenous Ligands 14
III. Expression of PACAP/VIP Receptors and Their Endogenous Ligands in the Adrenal Gland 18
IV. Effects of Endogenous Ligands of PACAP/VIP Receptors on Adrenal Cortex Secretion 22
V. Effects of Endogenous Ligands of PACAP/VIP Receptors on Adrenal Medulla Secretion 34
VI. Effects of Endogenous Ligands of PACAP/VIP Receptors on Adrenal Growth 40
VII. Concluding Remarks 41
Acknowledgments 43
References 43
Chapter 2: Ultrastructural Dynamics of Human Reproduction, from Ovulation to Fertilization and Early Embryo Development1 64
I. Introduction 65
II. Sperm Structure and Function 66
III. Human Mature Egg 76
IV. Gamete Interaction and Fertilization 100
V. The Embryo 120
VI. Concluding Remarks and Future Directions 134
Acknowledgments 136
References 136
Chapter 3: Chromosomal Variation in Mammalian Neuronal Cells: Known Facts and Attractive Hypotheses 154
I. Introduction 154
II. Numerical Chromosome Abnormalities: Origin and Consequences 155
III. Chromosomal Mosaicism in Humans 161
IV. Somatic Chromosomal Mosaicism in Mammalian Neuronal Cells 169
V. Relevance of Chromosomal Variations in the Mammalian Brain 181
VI. Technical Aspects of Studies of Chromosomal Mosaicism in Mammalian Neuronal Cells 187
VII. Concluding Remarks 192
Acknowledgments 194
References 194
Chapter 4: Automated Interpretation of Protein Subcellular Location Patterns 204
I. Introduction 205
II. Subcellular Location of Proteins 206
III. Subcellular Location Patterns of Proteins 210
IV. Concluding Remarks 234
Acknowledgments 235
References 235
Chapter 5: Cell and Molecular Biology of Human Lacrimal Gland and Nasolacrimal Duct Mucins 240
I. Introduction 241
II. Anatomy of the Lacrimal System 241
III. Properties of Mucins 245
IV. Lacrimal Gland Mucins 254
V. Mucins of the Nasolacrimal Ducts 268
VI. Conclusions and Perspectives 275
Acknowledgments 276
References 276
Index 292