Azaheterocycles Based on a,ß-Unsaturated Carbonyls (eBook)

Preface 5
Contents 7
Introduction 8
References 10
Three-Membered Azaheterocycles 12
1.1 Synthesis of Aziridinyl Ketones and Their Chemical Properties 12
1.2 Synthesis of Bi- and Tricyclic Aziridine Derivatives 22
1.3 Chemical Properties of Bi- and Tricyclic Aziridines 27
References 40
Five-Membered Azaheterocycles 44
2.1 Reactions with Diazoalkanes 44
2.2 Reactions of Hydrazines and Hydroxylamines 48
2.3 Structure, Chemical and Physicochemical Properties of Pyrazolines 57
References 62
Six-Membered Azaheterocycles Based on 1,3- Binucleophiles 68
3.1 Reactions of Enamines 69
3.2 Reactions of Urea and Its Analogues 72
3.3 Reactions of Malonic Acid Derivatives 83
3.4 Reactions of Aminoazoles 90
3.5 Reactions of Anilines and Aminoazines 107
3.6 Chemical Properties of Dihydroazines 115
3.7 Tautomerism of Pyridine and Pyrimidine Dihydro Derivatives 137
References 143
Cyclocondensations of 1,2-Diamines 155
4.1 Synthesis of 1,5-Dihydroazepines 155
4.2 Three-Component Condensation of 1,2-Diamines with Ketones 163
4.3 Reactions of Dihydrobenzodiazepines 169
4.4 Five- and Six-Membered Heterocycles Based on ortho- Diamines 176
References 182
Addendum: Selected Synthetic Procedures 187
A.1 Synthesis of Three-Membered Heterocycles 187
A.2 Synthesis of Five-Membered Heterocycles 193
A.3 Synthesis of Six-Membered Heterocycles 197
A.4 Reactions of a,b- Unsaturated Carbonyls with 1,2- Diamines 205
References 208
Index 210