Fetal Medicine

EARLY FETAL DEVELOPMENT 1.Early concepts and terminology 2.Cellular mechanisms and embryonic tissues 3.Staging embryos in development and the embryonic body plan 4.Development of the head 5.Development of the heart THE PLACENTA 6.The immunology of implantation 7.Development of the placenta and its circulation 8.Placental function and maternofetal exchange 9.Maternofetal trafficking FETAL PHYSIOLOGY AND PATHOLOGY 10.Development of the cardiovascular system 11. Lung growth and maturation 12. Development of the kidneys and urinary tract 13. Maternal medicines and the fetus 14. The perinatal postmortem EPIDEMIOLOGY 15.Epidemiological techniques in fetal medicine. ETHICS 16.Ethical issues in maternal-fetal medicine PRENATAL SCREENING AND DIAGNOSIS 17.Conveying information about screening 18.Parental reaction to prenatal diagnosis and subsequent bereavement 19.Prenatal screening for open neural tube defects and Down's syndrome 20.Ultrasound screening for fetal abnormalities and aneuploidies in the first and second trimesters 21.Non-invasive screening and diagnosis from maternal blood 22.Invasive diagnostic procedures 23.Cytogenetics 24.Mandelian genetics - the old and the new 25.Preimplantation genetic diagnosis 26.Haemaglobinopathies 27.Prenatal screening for thalassemias 28.Cystic fibrosis 29. Inborn errors of metabolism DIAGNOSIS AND MANAGEMENT OF FETAL MALFORMATIONS 30.Sonography of the fetal central nervous system 31. The heart 32.Fetal lung lesions 33.Congenital diaphragmatic hernia 34.Abdomen 35.Kidney and urinary tract disorders 36.Fetal skeletal abnormalities 37.Fetal hydrops 38.Fetal tumors DIAGNOSIS AND MANAGEMENT OF OTHER FETAL CONDITIONS 39.Fetal growth and growth restriction 40.Red cell alloimmunization 41.Fetal platelet disorders 42.Treatable fetal endocrine and metabolic disorders 43.Early pregnancy failure 44.Fetal infections 45.Amniotic fluid 46.Multiple pregnancy 47.In utero stem cell transplantation 48.Fetal gene therapy THE NEONATE 49.Interface of fetal and neonatal medicine Self-assessment scenarios Appendix: Charts of fetal measurements Index