Cerebral Vasospasm

New Strategies in Research and Treatment

Talat Kiris (Herausgeber)

Buch | Hardcover
XIII, 454 Seiten
2008 | 2008
Springer Wien (Verlag)
978-3-211-75717-8 (ISBN)

Lese- und Medienproben

Cerebral Vasospasm -
160,49 inkl. MwSt
This comprehensive volume is the current final word on the subject. It contains more than 90 papers, giving a summary of clinical and basic studies on cerebral vasospasm. It includes reviews by leading researchers in the field. Several new subjects are proposed for future research that will not only promote research from neurosurgery and neurology but also from other interconnecting fields of emergency medicine, electrophysiology, molecular biology, and vascular biology.

Advances in vasospasm research.- Advances in vasospasm research.- Vasospasm pathogenies.- Pre-vasospasm: early brain injury.- Apoptotic markers in vasospasm after an experimental subarachnoid haemorrhage.- Cerebrospinal fluid soluble Fas and Fas ligand levels after aneurysmal subarachnoid haemorrhage.- Time course of oxyhemoglobin induces apoptosis in mice brain cells in vivo.- Inhibition of c-Jun N-terminal kinase pathway attenuates cerebral vasospasm after experimental subarachnoid hemorrhage through the suppression of apoptosis.- Oxidative stress in subarachnoid haemorrhage: significance in acute brain injury and vasospasm.- Bilirubin oxidation products (BOXes): synthesis, stability and chemical characteristics.- Vascular contractility changes due to vasospasm induced by periarterial whole blood and thrombocyte rich plasma.- Vasospasm biochemistry.- Vasospasm biochemistry.- The roles of cross-talk mechanisms in the signal transduction systems in the pathophysiology of the cerebral vasospasm after subarachnoid haemorrhage what we know and what we do not know.- Subarachnoid hemorrhage induces upregulation of vascular receptors and reduction in rCBF via an ERK1/2 mechanism.- Effect of deferoxamine-activated hypoxia inducible factor-1 on the brainstem following subarachnoid haemorrhage.- Urgosedin downregulates mRNA expression of TNF-? in brain tissue of rats subjected to experimental subarachnoid haemorrhage.- Nucleotide-induced cerebral vasospasm in an in vivo mouse model.- Effects of ADPbetaS on purine receptor expression in mouse cerebral vasculature.- Vasospasm electrophysiology.- Electrophysiology of cerebral vasospasm.- Cellular basis of vasospasm: role of small diameter arteries and voltage-dependent Ca2+ channels.- Acute and chronic effects of oxyhemoglobin on voltage-dependent ion channels in cerebral arteries.- The effect of an intracisternal nimodipine slow-release system on cerebral vasospasm after experimental subarachnoid haemorrhage in the rat.- Cerebral vasospasm following subarachnoid haemorrhage is completely prevented by L-type calcium channel antagonist in human.- Vasospasm pharmacology.- Vasospasm pharmacology.- Endothelin-converting enzyme inhibitor versus cerebrovasospasm.- A pharmacokinetic study of clazosentan in patients with aneurysmal subarachnoid haemorrhage.- Pharmacokinetic and pharmacodynamic aspects of the interaction between clazosentan and nimodipine in healthy subjects.- Attenuation of intercellular adhesion molecule-1 and cerebral vasospasm in rabbits subjected to experimental subarachnoid haemorrhage by CGS 26303.- The effect of 17?-estradiol in the prevention of cerebral vasospasm and endothelin-1 production after subarachnoid haemorrhage.- Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.- An adenosine A1 receptor agonist preserves eNOS expression and attenuates cerebrovasospasm after subarachnoid haemorrhage.- Vasospasm molecular biology.- Gene transfer after subarachnoid hemorrhage: a tool and potential therapy.- Direct protein transduction method to cerebral arteries by using 11R: new strategy for the treatment of cerebral vasospasm after subarachnoid haemorrhage.- Endothelial nitric oxide synthase-11R protein therapy for prevention of cerebral vasospasm in rats: a preliminary report.- Microarray analysis of hemolysate-induced differential gene expression in cultured human vascular smooth muscle cells (HVSMC).- Vasospasm remodeling.- Role of vascular remodeling in cerebral vasospasm.- Possible role of tenascin-C in cerebral vasospasm after aneurysmal subarachnoid haemorrhage.- Ecdysterone-sensitive smooth muscle cell proliferation stimulated by conditioned medium of endothelial cells cultured with bloody cerebrospinal fluid.- The effect of oxyhemoglobin on the proliferation and migration of cultured vascular advential fibroblasts.- The effect of oxyhemoglobin on the proliferation and migration of cultured vascular smooth

Erscheint lt. Verlag 25.3.2008
Reihe/Serie Acta Neurochirurgica Supplement
Zusatzinfo XIII, 454 p.
Verlagsort Vienna
Sprache englisch
Maße 210 x 279 mm
Themenwelt Medizinische Fachgebiete Chirurgie Neurochirurgie
Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Radiologie
Schlagworte biochemistry • neural intensive care • Neurology • neurosurgery • subarachnoid hemorrhage • traumatic brain injury
ISBN-10 3-211-75717-1 / 3211757171
ISBN-13 978-3-211-75717-8 / 9783211757178
Zustand Neuware
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