Handbook of Free Radicals and Antioxidants in Biomedicine

Jaime Miquel, Ph.D. presently holds the position of Research Associate at the Linus Pauling Institute of Science and Medicine in Alicante. Alexandre T. Quintanilha, Ph.D., D.Sc., is Director of the Center for Atmosphere and Biospheric Effects of Technology and Assistant Head of the Applied Science Division at the Lawrence Berkeley Laboratory. Hans U. Weber, Ph.D., in 1987 joined the Medical Writing Group of Syntex Rsearch, Palo Alto, California.

Antioxidants and Free Radical Scavengers: Biochemical Mechanisms and Clinical Applications The Role of Antioxidants in the Function of the Adrenal Cortex. Essential Fatty Acids: Metabolism, Interaction with Free Radicals, and Clinical Use. Mechanisms of Antioxidant Action: Preventive and Chain-Breaking Antioxidants. The Role of Coenzyme Q in Free Radical Formation and Antioxidation. Induction by Substituted Phenols of Enzymes That Inactivate Electrophilic Compounds. Anti-Inflammatory Effects of Natural Phenolic Compounds. Centrophenoxine as OH. Free Radical Scavenger. Interactions between Vitamin C and E and Cytochrome P-450. Taurine and Hypotaurine and Membrane Lipid Peroxidation. The Physiological Functions of Glutathione. Effects of Exercise-Induced Oxidative Stress on Liver Glutathione. Vitamin E and Blood Cell Glutathione. Interaction between Antioxidant Vitamins C and E and Its Effect on Immune Responses. Effect of Vitamin E Status on Hepatic Cholesterol 7 α-Hydroxylase. Free Radical Lipid Peroxidation and Vitamin E in Liver Injury. Cytotoxic Actions of Isoproterenol in Cardiac Cell: Protective Effects of Antioxidants. Chronic Vitamin C Deficiency, Hypercholesterolemia, and Atherosclerosis. The Action of Free Radical Scavengers and Anti-inflammatory Drugs on Synovial Fluid Degradation Induced by Free Radicals. Α-Tocopherol and Plasma Lipids in Man. Effect of Vitamin E on Low-Density Lipoprotein Metabolism in the Arterial Wall. Serum α-Tocopherol, Coenzyme Q, and TBA-Reactive Substance in Acute Myocardial Damage and Stroke. Selenium and Lipid Peroxidation in Human and Experimental Cardiovascular Disease. The Neuropathology of Chronic Vitamin E Deficiency in Humans and Other Mammals. Synaptic Plasticity in the Cerebellar Glomeruli of Rats: Effects of Aging and Vitamin E Deficiency. Α-Tocopherol as a Potential Modifier of the Toxicity of Anthracycline Antibiotics. Antioxidant Therapy in Neuronal ceroid Lipofuscinosis (NCL). Consequences of Impaired Antioxidant Protection of the Retina. Vitamin E and Retinopathy of Prematurity. Pathogenesis and Antioxidant Suppression of Retinopathy of Prematurity. Pharmacological Protection against Free Radical-Induced Retrolental Fibroplasia.