Frontotemporal Dementias (eBook)

Emanuele Buratti is currently Group Leader of the Molecular Pathology Laboratory at the International Centre for Genetic Engineering and Biotechnology (ICGEB) in Trieste and Professor at the University of Trieste. Previously, he studied at the University of Trieste for a B.Sc. in Biology and a Ph.D. in Biochemistry. In 1995, he moved to ICGEB as a Staff Research Scientist. Dr. Buratti principal areas of expertise are the investigation of RNA binding proteins and RNA metabolism in neurodegeneration and metabolic diseases. On these subjects,  Emanuele Buratti is the author of more than 160 research papers in peer-reviewed publications and of book articles on these subjects (for a full list see orcid.org/0000-0002-1356-9074). He is Associate Editor at Frontiers in Genetics, Academic Editor at PloS ONE, and part of the Editorial Board at Journal of Biological Chemistry and Molecular and Cellular Neurosciences. He is also a member of the Scientific Committee of the Italian FTD Patient association (AIFTD) and an Expert Panel Member for Research Foundation Flanders (FWO). Homepage: http://www.icgeb.trieste.it/molecular-pathology.html

Dr. Brad Boeve is a consultant in the Department of Neurology and Center for Sleep Medicine at Mayo Clinic in Rochester, Minnesota, and is Professor of Neurology in the Mayo Clinic College of Medicine and Science. He also serves as Chair of the Division of Behavioral Neurology. His clinical and research interests include the non-Alzheimer's degenerative dementias and the neurologically-based sleep disorders, and particular interests in frontotemporal dementia +/- parkinsonism +/- ALS, primary progressive aphasia, corticobasal syndrome, and progressive supranuclear palsy/Richardson's syndrome, among other disorders. He is a member of the International Society for Frontotemporal Dementias, the Medical Advisory Council of the Association for Frontotemporal Degeneration, and the FTD Prevention Initiative. He is co-PI of Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS), co-investigator in the Advancing Research and Treatment in Frontotemporal Lobar Degeneration (ARTFL), and co-PI of the ARFTL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) Consortium. He is funded by the National Institute on Aging, National Institute of Neurological Disorders and Stroke, the Little Family Foundation, and the Mangurian Foundation.

Dr. Rosa Rademakers is Scientific Director of the VIB Center for Molecular Neurology and Professor of Neurogenetics at the Department of Biomedical Sciences at the University of Antwerp, Belgium, since 2019. Prior to that, she was Professor of Neuroscience at the Mayo Clinic in Jacksonville, Florida, where she still holds a position as Supplemental Consultant. Her research is focused on the molecular genetic analyses of neurodegenerative diseases, with a special interest in frontotemporal lobar degeneration and related neurodegenerative disorders. Her research program aims to provide new insights into disease pathogenesis and to identify novel targets for therapy through the discovery and subsequent study of novel disease genes. She leads the international FTLD-TDP whole genome sequencing consortium and is the co-lead of the Genetics Core of the ARFTL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) Consortium. She is the current President of the International Society for Frontotemporal Dementias and a member of the Medical Advisory Council of the Association for Frontotemporal Degeneration. She has received the Paolo Gontijo Medicine Award, the Sheila Essey Award for ALS Research and is the recipient of the 2016 Potamkin Prize for Research in Pick's, Alzheimer's and Related Disorders of the American Academy of Neurology.