Handbook of Experimental Pharmacology / Diuretics

This volume deals with the mechanisms of action of diuretics including cellular mechanisms of action, pharmacokinetics, and clinical usage. A major part focusses on most recent findings on the pharmacodynamics of the respective drugs. During the past twenty-five years since volume 14 on Diuretica was published in the Handbook series, the cellular mechanisms of action of diuretics have been unravelled. Today, the role of action within the target cells is known for most of the substances discussed. This has provided a new basis not only for the understanding of drug action but also for secondary effects and interactions. The book is a comprehensive reference work on the diverse groups of diuretics which are among the most frequently prescribed medications.