Harrisons Manual of Medicine

Dennis L. Kasper, MD, MA (Hon)William Ellery Channing Professor of MedicineProfessor of Microbiology and Molecular GeneticsExecutive Dean for Academic ProgramsHarvard Medical SchoolDirector, Channing LaboratoryDepartment of MedicineBrigham and Women’s Hospital Anthony S. Fauci, MDChief, Laboratory of ImmunoregulationDirector, National Institute of Allergy and Infectious DiseasesNational Institutes of Health. In 2008, Dr. Fauci was awarded the Presidential Medal of Freedom, the Nation's highest civil award. Stephen L. Hauser, MDChairman and Betty Anker Fife ProfessorDepartment of NeurologyUniversity of California, San Francisco Dan L. Longo, MDScientific DirectorNational Institute on AgingNational Institutes of HealthBethesda, Maryland C.F. Kettering Professor of Medicine, Chief, Division of Endocrinology, Metabolism and Molecular Medicine Northwestern University Medical School, Chicago, IL. Hersey Professor of the Theory and Practice of Medicine, Harvard Medical School; Chairman, Department of Medicine; Physician-in-Chief, Brigham and Women’s Hospital, Boston, Massachusetts

Contributors
Preface
Acknowledgments
SECTION 1 Care of the Hospitalized Patient
1 Electrolytes
2 Acid-Base Disorders
3 Diagnostic Imaging in Internal Medicine
4 Procedures Commonly Performed by Internists
5 Principles of Critical Care Medicine
6 Pain and Its Management
7 Assessment of Nutritional Status
8 Enteral and Parenteral Nutrition
9 Transfusion and Pheresis Therapy
10 Palliative and End-of-Life Care
SECTION 2 Medical Emergencies
11 Cardiovascular Collapse and Sudden Death
12 Shock
13 Narcotic Overdose
14 Sepsis and Septic Shock
15 Acute Pulmonary Edema
16 Acute Respiratory Distress Syndrome
17 Respiratory Failure
18 Confusion, Stupor, and Coma
19 Stroke
20 Subarachnoid Hemorrhage
21 Increased Intracranial Pressure and Head Trauma
22 Spinal Cord Compression
23 Hypoxic-Ischemic Encephalopathy
24 Status Epilepticus
25 Diabetic Ketoacidosis and Hyperosmolar Coma
26 Hypoglycemia
27 Oncologic Emergencies
28 Anaphylaxis
29 Bites, Venoms, Stings, and Marine Poisonings
SECTION 3 Common Patient Presentations
30 Fever, Hyperthermia, and Rash
31 Generalized Fatigue
32 Unintentional Weight Loss
33 Chest Pain
34 Palpitations
35 Dyspnea
36 Cyanosis
37 Cough and Hemoptysis
38 Edema
39 Abdominal Pain
40 Nausea, Vomiting, and Indigestion
41 Dysphagia
42 Diarrhea, Malabsorption, and Constipation
43 Gastrointestinal Bleeding
44 Jaundice and Evaluation of Liver Function
45 Ascites
46 Lymphadenopathy and Splenomegaly
47 Anemia and Polycythemia
48 Azotemia and Urinary Abnormalities
49 Pain and Swelling of Joints
50 Back and Neck Pain
51 Headache
52 Syncope
53 Dizziness and Vertigo
54 Acute Visual Loss and Double Vision
55 Weakness and Paralysis
56 Tremor and Movement Disorders
57 Aphasia
58 Sleep Disorders
SECTION 4 Otolaryngology
59 Sore Throat, Earache, and Upper Respiratory Symptoms
SECTION 5 Dermatology
60 General Examination of the Skin
61 Common Skin Conditions
SECTION 6 Hematology and Oncology
62 Examination of Blood Smears and Bone Marrow
63 Red Blood Cell Disorders
64 Leukocytosis and Leukopenia
65 Bleeding and Thrombotic Disorders
66 Myeloid Leukemias, Myelodysplasia, and Myeloproliferative Syndromes
67 Lymphoid Malignancies
68 Skin Cancer
69 Head and Neck Cancer
70 Lung Cancer
71 Breast Cancer
72 Tumors of the Gastrointestinal Tract
73 Genitourinary Tract Cancer
74 Gynecologic Cancer
75 Tumors of the Nervous System
76 Prostate Hyperplasia and Carcinoma
77 Cancer of Unknown Primary Site
78 Paraneoplastic Endocrine Syndromes
79 Neurologic Paraneoplastic Syndromes
SECTION 7 Infectious Diseases
80 Growing Threats in Infectious Disease
81 Infections Acquired in Health Care Facilities
82 Infections in the Immunocompromised Host
83 Infective Endocarditis
84 Intraabdominal Infections
85 Infectious Diarrheas and Bacterial Food Poisoning
86 Sexually Transmitted and Reproductive Tract Infections
87 Infections of the Skin, Soft Tissues, Joints, and Bones
88 Pneumococcal Infections
89 Staphylococcal Infections
90 Streptococcal/Enterococcal Infections, Diphtheria, and Infections Caused by Other Corynebacteria and Related Species
91 Meningococcal and Listerial Infections
92 Infections Caused by Haemophilus, Bordetella, Moraxella, and HACEK Group Organisms
93 Diseases Caused by Gram-Negative Enteric Bacteria and Pseudomonads
94 Infections Caused by Miscellaneous Gram-Negative Bacilli
95 Anaerobic Infections
96 Nocardiosis, Actin