Gene Therapy in Inflammatory Diseases
Springer Basel (Verlag)
978-3-7643-5855-6 (ISBN)
medicine. Edited by the undisputed pioneers of this area of research,
this volume is the first devoted to its topic. It contains thirteen
chapters, each written by leaders in their respective fields, that
summarize the state of the art in developing novel, gene based
treatments for inflammatory diseases. As well as providing an
introduction to the basic concepts of gene therapy and the use of naked
DNA approaches, the book describes the advances that have been made in
applying them to arthritis, lupus, multiple sclerosis, diabetes,
Sjogren`s syndrome and transplantation.One chapter is devoted to
discussing the first human clinical trials that apply gene therapy to
the treatment of an inflammatory disease. As well as providing novel
therapeutic approaches, gene therapy facilitates the development of new
and improved animal models of disease; a chapter describing these
advances is also included. As an up-to-date, timely book written by th
Gene therapy for inflammatory diseases is a new , burgeoning field of medicine. As an up-to-date, timely book written by the leaders in the field, this volume will appeal to both medical and graduate students, medical reseachers, members of the biotechnology community, physicians and all those interested in this latest frontier of molecular medicine.
Gene therapy for inflammatory diseases - basic concepts.- Gene therapy for rheumatoid arthritis: preclinical studies.- Cartilage erosion in rheumatoid arthritis: studies in SCID mouse model.- Gene therapy for rheumatoid arthritis: clinical studies.- Cytokine gene therapy of allergic airways inflammation.- Gene therapy for inflammatory diseases of the salivary glands.- Gene therapy for management of lupus: correction of Fas and Fas ligand-induced apoptosis in murine disease - therapeutic rationale and strategies.- Gene therapy for multiple sclerosis.- Gene therapy for type I diabetes mellitus.- Gene transfer to facilitate transplantation.- DNA vaccination as an anti-inflammatory strategy.- Naked DNA as a gene delivery vehicle in inflammatory diseases.- Animal models of arthritis generated by gene transfer.
| Erscheint lt. Verlag | 14.2.2000 |
|---|---|
| Reihe/Serie | Progress in Inflammation Research |
| Zusatzinfo | XII, 260 p. |
| Verlagsort | Basel |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 740 g |
| Themenwelt | Medizinische Fachgebiete ► Chirurgie ► Unfallchirurgie / Orthopädie |
| Schlagworte | Apoptosis • Arthritis • Cartilage • clinical trial • Cytokine • Development • DNA • genes • gene therapy • gene transfer • inflammation • Research • Rheumatoid Arthritis • Transplantation • Vaccination |
| ISBN-10 | 3-7643-5855-6 / 3764358556 |
| ISBN-13 | 978-3-7643-5855-6 / 9783764358556 |
| Zustand | Neuware |
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