Gene Therapy in Inflammatory Diseases -

Gene Therapy in Inflammatory Diseases

Buch | Softcover
XII, 260 Seiten
2012 | 1. Softcover reprint of the original 1st ed. 2000
Springer Basel (Verlag)
978-3-0348-9584-2 (ISBN)
160,49 inkl. MwSt
Gene therapy for inflammatory diseases is a new , burgeoning field ofmedicine. Edited by the undisputed pioneers of this area of research,this volume is the first devoted to its topic. It contains thirteenchapters, each written by leaders in their respective fields, thatsummarize the state of the art in developing novel, gene basedtreatments for inflammatory diseases. As well as providing anintroduction to the basic concepts of gene therapy and the use of nakedDNA approaches, the book describes the advances that have been made inapplying them to arthritis, lupus, multiple sclerosis, diabetes,Sjogren`s syndrome and transplantation.One chapter is devoted todiscussing the first human clinical trials that apply gene therapy tothe treatment of an inflammatory disease. As well as providing noveltherapeutic approaches, gene therapy facilitates the development of newand improved animal models of disease; a chapter describing theseadvances is also included. As an up-to-date, timely book written by th

Gene therapy for inflammatory diseases is a new , burgeoning field of medicine. As an up-to-date, timely book written by the leaders in the field, this volume will appeal to both medical and graduate students, medical reseachers, members of the biotechnology community, physicians and all those interested in this latest frontier of molecular medicine.

Gene therapy for inflammatory diseases - basic concepts.- Gene therapy for rheumatoid arthritis: preclinical studies.- Cartilage erosion in rheumatoid arthritis: studies in SCID mouse model.- Gene therapy for rheumatoid arthritis: clinical studies.- Cytokine gene therapy of allergic airways inflammation.- Gene therapy for inflammatory diseases of the salivary glands.- Gene therapy for management of lupus: correction of Fas and Fas ligand-induced apoptosis in murine disease - therapeutic rationale and strategies.- Gene therapy for multiple sclerosis.- Gene therapy for type I diabetes mellitus.- Gene transfer to facilitate transplantation.- DNA vaccination as an anti-inflammatory strategy.- Naked DNA as a gene delivery vehicle in inflammatory diseases.- Animal models of arthritis generated by gene transfer.

Erscheint lt. Verlag 22.11.2012
Reihe/Serie Progress in Inflammation Research
Zusatzinfo XII, 260 p.
Verlagsort Basel
Sprache englisch
Maße 155 x 235 mm
Gewicht 421 g
Themenwelt Medizinische Fachgebiete Chirurgie Unfallchirurgie / Orthopädie
Medizin / Pharmazie Studium
Schlagworte Apoptosis • Arthritis • Cartilage • clinical trial • Cytokine • Development • DNA • genes • gene therapy • gene transfer • inflammation • Research • Rheumatoid Arthritis • Transplantation • Vaccination
ISBN-10 3-0348-9584-4 / 3034895844
ISBN-13 978-3-0348-9584-2 / 9783034895842
Zustand Neuware
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