Alagille Syndrome (eBook)

Binita M. Kamath, MBBChir MRCP MTRThe Hospital for Sick ChildrenDivision of Gastroenterology, Hepatology and Nutrition Toronto, ONCanadaKathleen M. Loomes, MDChildren’s Hospital of PhiladelphiaDivision of Gastroenterology, Hepatology and NutritionDepartment of PediatricsPhiladelphia, PAUSA 

1 The Alagille Syndrome: Overview and IntroductionDavid Piccoli2 Bile Duct Development and the Notch Signaling PathwayStacey S. Huppert, Kathleen M. Campbell3 Genetics of Alagille SyndromeMelissa A. Gilbert, Nancy B. Spinner4 Liver Disease in Alagille SyndromeAlyssa Kriegermeier, Andrew Wehrman, Binita M. Kamath, Kathleen M. Loomes5 Transplant Considerations in Alagille SyndromeEvelyn Hsu, Elizabeth Rand6 Cardiac, Aortic, and Pulmonary Vascular Involvement in Alagille SyndromeJustin T. Tretter, Doff B. McElhinney7 Vascular Manifestations in Alagille SyndromeShannon M. Vandriel, Rebecca N. Ichord, Binita M. Kamath8 The Renal Sequelae of Alagille Syndrome as a Product of Altered Notch Signaling During Kidney DevelopmentRené Romero9 Skeletal Involvement in Alagille SyndromeYadav Wagley, Troy Mitchell, Jason Ashley, Kathleen M. Loomes, Kurt Hankenson10 Immune Dysregulation in Alagille Syndrome: A Feature of the Evolving PhenotypeAlastair Baker11 Health-Related Quality of Life and Neurocognition in Alagille SyndromeSaeed Mohammad, Estella M Alonso12 Future Therapeutic Approaches for Alagille Syndrome Emma R. Andersson