In Vivo Reprogramming in Regenerative Medicine -

In Vivo Reprogramming in Regenerative Medicine

Açelya Yilmazer (Herausgeber)

Buch | Hardcover
XVII, 103 Seiten
2017 | 1st ed. 2017
Springer International Publishing (Verlag)
978-3-319-65719-6 (ISBN)
106,99 inkl. MwSt
This new volume reviews current progress on different approaches of in vivo reprogramming technology. Leaders in the field discuss how in vivo cell lineage reprogramming can be used for tissue repair and regeneration in different organs, including brain, spinal cord, pancreas, liver and heart. Recent studies on in vivo cell reprogramming towards pluripotency are reviewed; examples are given to show its potential in regenerative medicine. In each chapter, the regenerative potential of different in vivo reprogramming approaches is discussed in detail. More specifically, how different tissue failures or damages can be treated with this technology is explained. Examples from various animal models are given and the regenerative potential of in vivo reprogramming is compared to that of cell transplantation studies. The last chapter discusses current challenges of these preclinical studies and gives suggestions in order to improve the current strategies. Future directions are indicated for the transition of in vivo reprogramming technology to clinical settings. This is among the first books in the literature which specifically focuses on the in vivo reprogramming technology in regenerative medicine and these chapters collectively cover one of the most important and exciting topics of regenerative medicine.

Dr. Açelya Yilmazer is as an assistant professor at the Biomedical Engineering Department and the vice director of the Stem Cell Institute of Ankara University. After receiving a BSc in Biology from the Middle East Technical University, she completed her MSc degree in Cancer Immunotherapy at the University of Nottingham and obtained her PhD in the Nanomedicine Lab based in the School of Pharmacy, University College London. She has been selected as the Best Young Investigator in Turkey by the Turkish Society of Medical Biology and Genetics. Her research laboratory focuses on cell reprogramming technologies and development of novel nanomaterial systems for directing cell fate. She is a member of the International Society of Stem Cell Research and the Biomaterials and Tissue Engineering Society of Turkey.

Chapter 1. Introduction to in vivo cell Reprogramming Technology.- Chapter 2. In vivo Reprogramming for Regenerating Insulin-Secreting Cells.- Chapter 3. Direct Reprogramming to Beta Cells.- Chapter 4. In vivo Lineage Reprogramming of Fibroblasts to Cardiomyocytes for Heart Regeneration.- Chapter 5: In vivo cell Reprogramming for Long-term Pluripotency.- Chapter 6: In vivo Transient Reprogramming Towards Pluripotency for Tissue Repair and Regeneration.- Chapter 7. Challenges and Future Perspectives for in vivo Reprogramming Technology.

Erscheinungsdatum
Reihe/Serie Stem Cell Biology and Regenerative Medicine
Zusatzinfo XVII, 103 p. 15 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Gewicht 355 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Biomedizin
Medizin / Pharmazie Medizinische Fachgebiete Chirurgie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte Biomedical and Life Sciences • Brain Repair • Cardiomyocyte Regeneration • Cell Culture • cell lineage • cellular biology (cytology) • Dedifferation • Genetics (non-medical) • Life sciences: general issues • Regenerative Medicine/Tissue Engineering • spinal cord injury • Stem Cells • Tissue repair • Transplant Surgery
ISBN-10 3-319-65719-4 / 3319657194
ISBN-13 978-3-319-65719-6 / 9783319657196
Zustand Neuware
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