The Molecular Basis of Blood Disease

Provides a base for both research scientists and clinicians to keep abreast of developments in this field. Coverage includes thalassaemia syndromes, sickle cell anaemia, oncogenesis and cancer viruses, haemoglobin switching, histocapatability genes and antigens, and other topics.

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The first edition of the Molecular Basis of Blood Diseases was the first book ever to attempt a collation and defininition of the cellular and molecular bases of hamatology. The attempt was very successful, and received rave reveiws from JAMA, The New England Journal of Medicine, the Cancer Bulletin, and the Annals of Internal Medicine. The superb new second edition covers all the groundbreaking developments which have taken place in this field since the publication of the first edition. Comprehensively revised, it presents all the newest findings on the molecular bases of blood cell functions and disease mechanisms...and the impact of these discoveries on the state of medicine. Features: * Offers the very latest information on gene regulatory mechanisms, including transcriptional control and splicing, hemoglobin switching, the thalassemias, hematopoiesis and lymphopoiesis, sickle, hemoglobin, white blood cell disorders, viruses, including HTLVs and much, much more! * Includes contributions by 38 of the leading names in the field. Their expertise spans every area of the specialty and so does the coverage they provide.