Head and Neck Cancer (eBook)

Multimodality Management

Jacques Bernier (Herausgeber)

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2016 | 1st ed. 2016
XXI, 878 Seiten
Springer International Publishing (Verlag)
978-3-319-27601-4 (ISBN)

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​This second edition ​provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management. 

Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks. 

In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome. 



After obtaining his degree in Radio-Oncology at the University of Liege, Belgium, Jacques Bernier completed his training at the MD Anderson Cancer Center, Houston, and the Curie Institute, Paris. In 2006 he joined the Swiss Genolier Medical Network, where since then he has been chairing the Radio-Oncology Department. Throughout most of his career, Jacques Bernier has been heavily involved with translational and clinical research. From 2000 to 2006 Jacques Bernier was Chairman of the Head and Neck Group of the EORTC. He currently serves as an Editorial Board member of various international peer-reviewed journals, including 'Journal of Clinical Oncology'. He is an Associate Editor of 'Annals of Oncology' (since 2010), and 'Oral Oncology' (since January 2011). A Course Director at the European School of Oncology since 1990, Jacques Bernier is also the Chairman of the International Conference on Translational Research in Radio-Oncology - ICTR, organized every three years in Switzerland. He serves as a regular member of advisory boards for many pharmaceutical companies. He is President of the Foundation for the Advancement of Radiation Oncology - FARO, in Geneva, member of the Executive Board of Euro-Asian Society of Mastology - EURAMA, Board of Trustees of 'Science for Peace' and Scientific Committee of the 'Umberto Veronesi Foundation' in Milan.

After obtaining his degree in Radio-Oncology at the University of Liege, Belgium, Jacques Bernier completed his training at the MD Anderson Cancer Center, Houston, and the Curie Institute, Paris. In 2006 he joined the Swiss Genolier Medical Network, where since then he has been chairing the Radio-Oncology Department. Throughout most of his career, Jacques Bernier has been heavily involved with translational and clinical research. From 2000 to 2006 Jacques Bernier was Chairman of the Head and Neck Group of the EORTC. He currently serves as an Editorial Board member of various international peer-reviewed journals, including “Journal of Clinical Oncology”. He is an Associate Editor of “Annals of Oncology” (since 2010), and “Oral Oncology” (since January 2011). A Course Director at the European School of Oncology since 1990, Jacques Bernier is also the Chairman of the International Conference on Translational Research in Radio-Oncology - ICTR, organized every three years in Switzerland. He serves as a regular member of advisory boards for many pharmaceutical companies. He is President of the Foundation for the Advancement of Radiation Oncology – FARO, in Geneva, member of the Executive Board of Euro-Asian Society of Mastology - EURAMA, Board of Trustees of “Science for Peace” and Scientific Committee of the “Umberto Veronesi Foundation” in Milan.

Table of ContentsHead and Neck Cancer: Multimodality Management, 2nd EditionEditors: Jacques BernierCh. 1: Epidemiology and Aetiology of Head and Neck CancersNewell W. JohnsonHemantha K. AmarasingheCh. 2: Head and Neck Cancer PreventionFausto ChiesaAngelo OstuniRoberto GrigolatoLuca CalabreseMohssen AnsarinCh. 3: Cellular and Molecular Pathology of Head and Neck TumorsAdel K. El-NaggarCh. 4: Oncogenomics/Proteomics of Head and Neck CancersJason I. KassHoward S. MoskowitzJennifer R. GrandisCh. 5: Genetics and Epigenetics of Head and Neck CancerJagtar DhandaRichard J. ShawCh. 6: Immunology of Head and Neck CancerBenjamin A. KansySteve C. LeeRobert L. FerrisCh. 7: Biomarkers in Head and Neck CancerHyunseok KangChristine H. ChungArlene A. ForastiereCh. 8: HPV and EBV in Head and Neck CancerJeffrey BrumbaughRobert L. FerrisShen HuCh. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCCBrian O’SullivanJatin P. ShahWilliam M. LydiattCh. 10: Preclinical Models of Head and Neck Squamous Cell CarcinomaC.L. ZuurA.J.C. DohmenMichiel W. van den BrekelXiao-Jing WangStephen MalkoskiCh. 11: Translational Research in Head and Neck OncologyDavid S. YooDavid M. BrizelCh. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and TreatmentYungan TaoJean BourhisCh. 13: Imaging of Head and Neck CancersTaha S. MerajSuyash MohanGaurang V. ShahCh. 14: Ultrasound Investigations in Head & Neck Cancer PatientsYolanda Y.P. LeeKa Tak WongKunwar Suryaveer Singh BhatiaAnil Tejbhan AhujaCh. 15: Sentinel Node BiopsyOliver J. SmithLee W.T. AlkureishiGary L. RossCh. 16: Intensity-Modulated Radiation Therapy for Head and Neck CancerMarsha ReyngoldEdward J. ShinNancy LeeCh. 17: Stereotactic Radiotherapy in Head and Neck Cancer PatientsThomas LeroyEric LartigauCh. 18: Proton Beam Therapy for Head and Neck CancerDanielle N. MargalitJudy A. AdamsHanne M. KooyAnnie W. ChanCh. 19: Principles of Systemic Chemotherapy for Squamous Cell Head and Neck CancerCristina P. RodriguezDavid J. AdelsteinCh. 20: Molecular Targeted Therapies in Head and Neck CancerZachary S. MorrisAnne M. TraynorPaul M. HarariCh. 21: Laser Endoscopic TreatmentPierre MoreauPierre DemezCh. 22: Transoral robotic surgery in head and neck cancerSylvain Morinière Ch. 23: Multidisciplinary Management of Skull Base and Superstructure TumorsGiulio CantùCarlo L. SoleroStefano RiccioSarah ColomboMadia PompilioCh. 24: Multidisciplinary management of oral cavity and maxillary sinus cancersAlexander D. RapidisCh. 25: Oral OncologyRuth Aponte WessonTheresa M. HofstedeRichard C. CardosoPattii MontgomeryAlexander M. WonJack W. MartinMark S. ChambersCh. 26: Management of Nasopharyngeal CarcinomaWai Tong NgRoger K.C. NganSiu Hong ChanHenry SzeJimmy Y.W. ChanAnne W.M. LeeCh. 27: Multidisciplinary management of oropharynx carcinomasBeth M. BeadleDavid I. RosenthalCh. 28: Multidisciplinary Management of Hypopharyngeal CarcinomaMarc HamoirJean-Pascal MachielsSandra SchmitzVincent GregoireCh. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and ManagementCarol M. LewisSteven B. ChinnChris HolsingerRandal S. WeberCh. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal CancersNabil F. SabaJ. Trad WadsworthJonathan J. BeitlerFadlo R. KhuriCh. 31: Programs of Organ and Function PreservationJean Louis LefebvreCh. 32: Principles and New Approaches in Surgical ReconstructionAndreas DietzMilos FischerChristina MagillBruce H. HaugheyCh. 33: Multidisciplinary treatment of the neckRemco de BreeJohannes A. LangendijkC.R. LeemansCh. 34: Postoperative Management of High-Risk Resectable Head and Neck CancerAssuntina G. SaccoEzra E. CohenCh. 35: Multidisciplinary Approach of Unresectable Head and Neck CancerRicardo HittAna Lopez-MartinJuan J. CruzRobert I. HaddadCh. 36: Management of Salivary Gland CancerLaura D. LocatiMarco GuzzoEster OrlandiLisa LicitraCh. 37: Primary Mucosal Melanomas of the Head and NeckJuliette ThariatAnne-Catherine BaglinPierre Yves MarcyCaroline EvenAntoine Moya-PlanaYusuke DemizuAdam S. GardenMarco KrengliMichael A. PostowCh. 38: Head & Neck Cutaneous MelanomaMina N. LeMichael A. PostowSnehal G. PatelCh. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary SiteNicholas PavlidisGeorgios PlataniotisCh. 40: The Management of Thyroid and Parathyroid CancerNasheed M. HossainColleen VeloskiRanee MehraCh. 41: Head and Neck ParagangliomasJulian KünzelMichael HainzHeidi RossmannChristoph MatthiasCh. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckPetr SzturzJan B. VermorkenCh. 43: Phase I study methodology in head and neck oncologyAaron HansenChristophe Le TourneauCh. 44: Treatment of the Elderly Head and Neck Cancer PatientJean-Claude HoriotMatti AaproCh. 45: Normal Tissue Complications and Protection in Head and Neck Cancer PatientsAndy TrottiNikhil RaoAvraham EisbruchDavid I. RosenthalCh. 46: Advances in Management of Complications for Head and Neck Cancer TherapyBarbara MurphyJie DengMark J. StavasHeidi GanzerJoel B. EpsteinCh. 47: Rehabilitation of Heavily Treated Head and Neck Cancer PatientsKatherine A. HutchesonCh. 48: Salvage Therapy in Head and Neck Cancer PatientsJohn HeaphyRod RezaeePierre LavertuCh. 49: Quality of Life in Head and Neck Cancer PatientsJolie RingashCh. 50: Psycho-oncologic aspects of head and neck cancer patientsMichel ReichCh. 51: Advances in Nanomedicine for Head and Neck CancerSajanlal R. PanikkanvalappilMostafa A. El-SayedIvan H. El-SayedCh. 52: Head and Neck Quality Assurance 2014Thomas J. FitzGeraldMaryann Bishop-JodoinDavid S. FollowillJames M. GalvinMichael V. KnoppJeff M. MichalskiMark RosenJonathan M. GlanzmanPaul RavaAllison SacherDavid J. GoffAlec VaeziKenneth Ulin

Erscheint lt. Verlag 22.8.2016
Zusatzinfo XXI, 878 p. 337 illus., 250 illus. in color.
Verlagsort Cham
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete
Schlagworte bio-radiation • head and neck cancer • Head and Neck Surgery • Oncology • Otolaryngology • otorhinolaryngology • radiotherapy
ISBN-10 3-319-27601-8 / 3319276018
ISBN-13 978-3-319-27601-4 / 9783319276014
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