Short Course Breast Radiotherapy (eBook)

Dr. Arthur is currently Professor and Vice Chairman of the  Department of Radiation Oncology , Virginia Commonwealth University. His clinical and research interests include brachytherapy, management of breast and genitourinary malignancies, and soft tissue malignancies. Dr Arthur’s primary research interests include clinical studies focusing on the treatment of breast cancer with special interest in the development and use of accelerated treatment for breast cancer.  He is a breast committee member of the NRG Oncology national cooperative trial group.   Dr. Frank Vicini has held multiple academic appointments and authored over 200 peer-reviewed articles. He is involved in numerous clinical studies being the Principal Investigator of several with the goal of improving therapeutic outcomes for all stages of breast cancer, reducing cancer treatment times and minimizing toxicities of healthy tissues and vital organs. He is also listed as one of the few oncologists in "Best Oncology Doctors in America."David E. Wazer, MD is chief of radiation oncology for the Lifespan Healthcare System in New England and divides his time between Rhode Island Hospital and Tufts Medical Center in Boston. He is professor and chairman of radiation oncology at both Tufts University School of Medicine and The Alpert Medical School of Brown University. Dr. Wazer has numerous scientific publications, co-edits the premier textbook for radiation oncology,  serves as Editor-in-Chief of the American Journal of Clinical Oncology, and actively conducts clinical and cost/utility research in breast cancer, brachytherapy, melanoma, and several novel radiation therapy technologies. Dr. Khan has been at the Cancer Institute of New Jersey since 2007 after completing a fellowship in brachytherapy at the Brigham and Women’s Hospital at Harvard. Prior to that, he completed a residency in radiation oncology at Rush University Medical Center. Dr. Khan’s primary focus has been in breast cancer, as well as radiation therapy for central nervous system/brain tumors.  Dr Khan is interested in the discovery of novel radiosensitizers and in advanced modalities of highly conformal radiotherapy, such as image-guided brachytherapy and proton therapy.   

Section I: 1.Accelerated Breast Irradiation: History, Rationale, and Controversies 2.Pathologic Anatomy of Early-Stage Breast Cancer: Defining the Target 3.The Radiobiology of Accelerated Breast Irradiation 4.Quality Assurance and Radiation Safety/Medical Events  5.Surgical Considerations in Partial Breast Irradiation 6.Impact of Oncoplastic Surgery on adjuvant XRT 7. Comparison of true cost between modalities in a changing health care system SECTION II:  Hypofractionated WBI 8. Patient Selection 9. Physics of HWBI 10. Treatment History- techniques/data/toxicity SECTION III: APBI 11. Patient Selection 12. Physics of Accelerated Partial Breast Irradiation 13. Interstitial brachytherapy – techniques/data/toxicity                                         14. Intracavitary brachytherapy – techniques/data/toxicity 15. 3D-Conformal external beam radiotherapy  - techniques/data/toxicity SECTION IV: IORT 16. Patient Selection 17. Physics of IORT 18. 50 kV Photons: Targeted Intraoperative Radiotherapy (TARGIT) - techniques/data/toxicity 19. Intraoperative Technique with Electrons-  techniques/data/toxicity SECTION V: Emerging treatment approaches              20. Extreme hypofractionation (brachytherapy, Gammapod, UK FAST WBI)                21. APBI for breast augmentations               22. Accuboost                 23. APBI for in-breast recurrence following WBI                           24. Preoperative partial breast 25.  Locoregional Hypofractionation SECTION VI: Hypofractionation for metastatic disease 26.Stereotactic treatment for Oligometastatic disease 27.Hypofractionaton for palliationBone mets - palliativeVisceral mets - palliativeChest wall/localregional recurrence