Childhood Leukemias
Cambridge University Press (Verlag)
978-0-521-58176-9 (ISBN)
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Childhood leukemias represent nearly one third of all cancers in children and present a unique challenge to oncologists, pediatricians, hematologists, and other health professionals. Dr Ching-Hon Pui has assembled an expert team of authors to develop the most comprehensive, clinically-oriented, and authoritative reference dedicated to these diseases. Childhood Leukemias moves from the laboratory bench to the patient bedside in three easily-accessible sections. Part one presents an in-depth review of topics needed to understand the pathobiology of leukemia. Part two builds upon this scientific foundation by explaining practical approaches to clinical diagnosis, evaluation, and treatment. The final section outlines major clinical complications which arise during and after treatment. Chapters on supportive care, psychosocial issues, and nursing will also interest general practitioners and nurses. The entire text is supplemented by numerous tables and figures. Fully referenced and up-to-date, Childhood Leukemias is an absolute 'must-have' for any physician or investigator who deals with leukemias in childhood.
Introduction; 1. Historical perspective Donald Pinkel; 2. Diagnosis and classification David R. Head and Ching-Hon Pui; 3. Epidemiology and etiology Smita Bhatia, Julie A. Ross, Mel F. Greaves and Leslie L. Robinson; Part I. Cell Biology and Pathobiology: 4. Anatomy and physiology of hematopoiesis Connie J. Eaves and Allen C. Eaves; 5. Hematopoetic growth factors James N. Ihle; 6. Signal transduction in the regulation of hematopoiesis James N. Ihle; 7. Immunophenotyping Fred G. Behm and Dario Campana; 8. Immunoglobulin and T-cell receptor gene rearrangements Anton W. Langerak and Jacques J. M. Van Dongen; 9. Cytogenetics of acute leukemias Susana C. Raimondi; 10. Molecular genetics of acute lymphoblastic leukemia Jeffrey E. Rubnitz and A. Thomas Look; 11. Molecular genetics of acute myeloid leukemia James R. Downing; 12. Apoptosis and chemoresistance John C. Reed; Part II. Evaluation and Treatment: 13. Pharmacokinetic and pharmacodynamics consideration Michael H. Woo, William E. Evans and Mary V. Relling; 14. Acute lymphoblastic leukemia Ching-Hon Pui and William M. Crist; 15. B-Cell acute lymphoblastic leukemia and Burkitt's lymphoma John T. Sandlund and Ian Magrath; 16. Acute myeloid leukemia Howard J. Weinstien; 17. Chronic myelodysplastic syndromes and chronic myeloproliferative disorders Maurizio Arico and Andrea Biondi; 18. Hematopoietic stem cell transplantation Jean E. Sanders; 19. Adoptive cellular immunotherapy Helen E. Heslop and Cliona M. Rooney; 20. Methods and applications of gene transfer Malcolm Brenner; 21. Testing new therapeutic agents Dario Campana, Peter J. Houghton and Gaston K. Rivera; 22. Minimal residual disease Dario Campana, Jacques J. M. Van Dongen and Ching-Hon Pui; Part III. Complications and Supportive Care: 23. Acute complications Raul Correa Ribeiro and Ching-Hon Pui; 24. Late complications Melissa M. Hudson; 25. Infectious complications Walter T. Hughes; 26. Hematologic supportive care Victor M. Santana; 27. Psychosocial issues Raymond K. Mulhern, Sean Phipps and Vida L. Tyc; 28. Nursing care Pamela S. Hinds and Jami S. Gattuso.
| Erscheint lt. Verlag | 13.8.1999 |
|---|---|
| Zusatzinfo | 94 Tables, unspecified; 40 Plates, color; 51 Halftones, unspecified; 75 Line drawings, unspecified |
| Verlagsort | Cambridge |
| Sprache | englisch |
| Maße | 223 x 288 mm |
| Gewicht | 1865 g |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hämatologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pädiatrie | |
| ISBN-10 | 0-521-58176-1 / 0521581761 |
| ISBN-13 | 978-0-521-58176-9 / 9780521581769 |
| Zustand | Neuware |
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