UICC Manual of Clinical Oncology (eBook)

Foreword x

Preface xi

About the Editors xiii

Contributors xvi

PART 1 General principles of cancer diagnosis and management 1

Principles of knowledge generation and translation

1 - Cancer epidemiology 3

2 - Levels of evidence, guidelines and standards 12

3 - Prognosis and classification of cancer 23

4 - Principles of cancer staging 34

5 - Assessment of treatment outcome 40

6 - Cancer informatics 53

Principles of cancer diagnosis

7 - Imaging 63

8 - Pathology 83

Principles of treatment

9 - Principles of surgery 98

10 - Principles of radiotherapy 108

11 - Principles of systemic therapy 124

Special settings, supportive care and survivorship

12 - Treatment in pregnancy 134

13 - Treatment in the elderly 139

14 - Oncology emergencies 145

15 - Supportive care during curative treatment 155

16 - Pain management in cancer 168

17 - Palliative care 174

18 - Survivorship 184

19 - Rehabilitation 194

PART 2 Site-specific multidisciplinary cancer management 203

Thoracic malignancies

20 - Lung 205

Breast

21 - Breast 221

Gastrointestinal malignancies

22 - Liver 241

23 - Biliary tract and pancreas 263

23.1 - Biliary tract 263

23.2 - Pancreas 270

24 - Oesophagus 280

25 - Stomach 297

26 - Colon, rectum and anus 308

26.1 - Colon and rectum 308

26.2 - Anus 327

Genitourinary malignancies

27 - Prostate 333

28 - Bladder and other urothelium 343

29 - Kidney 354

30 - Testicular germ cell tumours 368

31 - Penis 384

Haematological malignancies

32 - Lymphoma 392

33 - Myeloma 415

34 - Leukaemia 427

Gynaecological cancers

35 - Cervix 449

36 - Uterus 467

37 - Ovary and fallopian tube 479

Head and neck cancer

39 - General principles of head and neck cancer management 503

40 - Nasopharynx 512

41 - Oral cavity 524

42 - Larynx and hypopharynx 542

43 - Oropharynx 559

44 - Major salivary glands 571

45 - Nasal cavity and paranasal sinus 586

46 - Head and neck unknown primary 597

Endocrine tumors

47 - Pituitary 609

48 - Thyroid 626

49 - Adrenal tumours 641

50 - Neuroendocrine tumours 656

Dermatological cancer

51 - Skin: Basal cell carcinoma, squamous cell carcinoma and Merkel cell carcinoma 674

52 - Melanoma 689

Central nervous system and ocular cancers

53 - Central nervous system 706

54 - Eye: Choroidal melanoma, retinoblastoma, ocular adnexal lymph

Sarcoma

55 - Bone (osteosarcoma) 745

56 - Soft tissue 754

Childhood malignancies

57 - Paediatric tumors 768

Specific cancer situations

58 - Cancer of unknown primary (no 59 - HIV and transplant-related neoplasms 797

59.1 - HIV-related neoplasms 797

59.2 - Post-transplantation lymphoproliferative disease 809

59.3 - Cancer following solid organ transplantation 812

Index 815