Nutrition, Immunity, and Infection

Mechanisms of Interactions

R. K. Chandra, P. M. Newberne (Autoren)

Buch | Softcover

264 Seiten

2012 | Softcover reprint of the original 1st ed. 1977
Springer-Verlag New York Inc.
978-1-4684-0786-0 (ISBN)

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I welcome the privilege of writing some words of introduction to this important book. Its authors have been courageous in bringing together in one text a triad of topics that cover such large tracts of biomedical sciences as epidemiology, biochemistry, immunology, and clinical medicine. Malnutrition and infection are known to be closely linked, the one promoting the other. The adaptive immune system forms a part of the link since it is responsible for a good deal of defense against infection, and it may be affected adversely by malnutrition and indeed by infection itself. Knowledge in this complex field is of great potential importance because malnutri tion and infection are such dominant features of the ill-health of many of the world's underprivileged people. As this book shows, there is no lack of technical facets for study. There are now so many components of the immune response which can be measured or assessed and so many aspects of nutritional biochemistry which can be studied that the problem is to select what to study and where to begin. Moreover, the great number of variables in the nature of nutritional deficiencies, in types of infections or multiple infections and in the genetic, environmental, and social background of the affected people, all combine to make interpretation and application of findings a speculative business. Descriptions of cause and effect must us ually be provisional rather than definitive.

1. Introduction.- 2. Mechanisms of Host Defense.- 2.1. Ontogenetic Development of Antigen-Specific Immunity.- 2.2. Phagocytes.- 2.3. Complement System.- 2.4. Other Factors of Host Resistance.- 2.5. Concluding Remarks.- 3. Assessment of Nutritional Status.- 3.1. Energy-Protein Undernutrition.- 3.2. Vitamin and Mineral Deficiencies.- 3.3. Fetal Malnutrition.- 3.4. Concluding Remarks.- 4. Infections in Undernourished Individuals.- 5. Nutritional, Metabolic, and Immunologic Effects of Infection.- 5.1. Nutritional Consequences of Infection.- 5.2. Metabolic and Hormonal Responses during Infection.- 5.3. Immune Responses in Infection.- 6. Immunocompetence in Undernutrition.- 6.1. Lymphoid Tissues.- 6.2. Cell-Mediated Immunity.- 6.3. Immunoglobulins and Antibodies.- 6.4. Complement System.- 6.5. Phagocytes.- 6.6. Lysozyme.- 6.7. Iron-Binding Proteins.- 6.8. Tissue Integrity.- 6.9. Interferon.- 6.10. Other Factors.- 7. Interactions of Nutrition, Infection, and Immune Response in Animals.- 7.1. General Considerations.- 7.2. Nutrition-Infection Interactions.- 7.3. Summary.- 8. Biological Implications.- 8.1. Infection-Related Morbidity and Mortality.- 8.2. Postoperative Sepsis.- 8.3. Parenteral Hyperalimentation and Infection.- 8.4. Intergenerational Effects of Undernutrition, Impaired Immunocompetence, and Infection.- 8.5. Nutritional Deficiency, Immunopathologic Disease, and Aging.- 8.6. Cancer.- 8.7. Autoimmunity and Allergy.- 8.8. Food Antibodies.- 8.9. Prophylactic Immunization.- 8.10. Immunopotentiation in Management of Malnutrition-Infection Syndrome.- 8.11. Obesity.- 9. Future Research Needs.- References.

Erscheint lt. Verlag	22.2.2012
Zusatzinfo	29 Illustrations, black and white; 264 p. 29 illus.
Verlagsort	New York, NY
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Gesundheitsfachberufe ► Diätassistenz / Ernährungsberatung
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	1-4684-0786-4 / 1468407864
ISBN-13	978-1-4684-0786-0 / 9781468407860
Zustand	Neuware