Recurrent Pregnancy Loss (eBook)

Ole Bjarne Christiansen, MD, PhD, Professor of Obstetrics and Gynecology, Fertility Clinic, Rigshospitalet, Copenhagen, Denmark.

Series Foreword vii

Contributors viii

Preface to the first edition xii

1 Obtaining the Relevant History 1

Ole B. Christiansen

2 Which Investigations Are Relevant? 10

Paulien G. de Jong, Emmy van den Boogaard, Claudia R. Kowalik,
Rosa Vissenberg, Saskia Middeldorp and Mariëtte
Goddijn

3 NK Cells in Peripheral Blood and the Endometrium 29

Gavin Sacks

4 Cytokines and Cytokine Gene Polymorphisms in Recurrent
Pregnancy Loss 38

Silvia Daher, Maria Regina Torloni and Rosiane Mattar

5 How to Assess the Prognosis after Recurrent Miscarriage
46

Howard J.A. Carp

6 Which Treatments Should be Offered? PGD/PGS, Allogeneic
Lymphocyte Immunization, Intravenous Immunoglobulin 61

Henriette Svarre Nielsen and Ole B. Christiansen

7 Which Treatment Should be Offered? Heparin/Aspirin,
Progesterone, Prednisolone 70

Muhammad A. Akhtar and Siobhan Quenby

8 Which Treatment Should be Offered: Metformin, hCG,
GM-CSF/G-CSF, TNF-alpha Inhibitors, Standard IVF/ICSI 78

Ole B. Christiansen

9 Talking to Patients about Lifestyle, Behavior, and Miscarriage
Risk 86

Ruth Bender Atik and Barbara E. Hepworth-Jones

10 E ndocrine and Ultrasonic Surveillance of Pregnancies in
Patients with Recurrent Miscarriage 103

Adjoa Appiah and Jemma Johns

11 Obstetric Complications in Patients with Recurrent
Miscarriage - How Should they be Monitored

in the Third Trimester? 115

Shehnaaz Jivraj

12 Recurrent Miscarriage after ART: A Double Challenge 128

Elisabeth C. Larsen and Ole B. Christiansen

13 How to Cope with Stress and Depression in Women with
Recurrent Miscarriage 135

Keren Shakhar and Dida Fleisig

14 Recurrent Miscarriage and the Risk of Autoimmune Disease and
Thromboembolic Disease 146

M. Angeles Martínez-Zamora, Ricard Cervera and Juan
Balasch

15 How to Organize and Run an Early Pregnancy Unit/Recurrent
Miscarriage Clinic 157

AnnMaria Ellard and Roy G. Farquharson

16 How to Organize an Early Pregnancy Unit/Recurrent Miscarriage
Clinic - American Perspective 172

Joanne Kwak-Kim, Kuniaki Ota and Ae-Ra Han

17 Case Studies 180

Ole B. Christiansen

Index 191