Emerging Trends in Cell and Gene Therapy (eBook)

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2013 | 2013
XVII, 705 Seiten
Humana Press (Verlag)
978-1-62703-417-3 (ISBN)

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Emerging Trends in Cell and Gene Therapy -
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Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry.

 

Main features of the book:

·         Biological aspects of stem cell sources, differentiation and engineering.  

·         Application of microfluidics to study stem cell dynamics

·         Potential clinical application of stem cells and gene therapy to specific human disease.

·         Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering.

·         Biomimetic multiscale topography for cell alignment.


Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry. Main features of the book:* Biological aspects of stem cell sources, differentiation and engineering. * Application of microfluidics to study stem cell dynamics* Potential clinical application of stem cells and gene therapy to specific human disease. * Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering. * Biomimetic multiscale topography for cell alignment.

1. The Mechanism of Stem Cell Differentiation into SmoothMuscle CellsRussell Simpson and Qingbo Xu  2. Recent Advances in Embryonic Stem Cell Engineering Towards Tailored “Lineage DifferentiationZhen Xu, Jingyu Wang, and Yanan Du3. Human Amniotic Membrane: A Potential Tissue and Cell Source for Cell Therapy and Regenerative MedicineSilvia Diaz-Prado, Emma Muiños-Lopez, Isaac Fuentes-Boquete, Francisco J. de Toro, and Francisco J Blanco Garcia4. Novel Strategies Applied to Provide Multiple Sources of Stem Cells as a Regenerative Therapy for Parkinson’s DiseaseAbir O. El Sadik5. Hair Follicle: A Novel Source of Stem Cells for Cell and Gene TherapyPanagiotis Mistriotis and Stelios T. Andreadis 6. Genetically Modified Stem Cells for TransplantationM. Ian Phillips7. Induced Pluripotent Stem Cells: Basics, and the Application in Disease Model and Regenerative MedicineZhiyong Liu  and Feng Li 8. Gene Transfer to the Heart. Emerging Strategies for the Selection of Vectors, Delivery Techniques and Therapeutic TargetsMichael G Katz, Anthony S Fargnoli, Louella A Pritchette, Charles R BridgesCarolinas Healthcare System9. Cell-Based Therapy for Cardiovascular InjuryYuji Haraguchi, Tatsuya Shimizu, Masayuki Yamato and Teruo Okano 10. Induced Pluripotent Stem Cells: New Advances in Cardiac Regenerative MedicineShinsuke Yuasa, Mitsushige Murata, and  Keiichi Fukuda11. Dendritic Cells for Cancer ImmunotherapyNicolas Larmonier  and Emmanuel Katsanis 12. Mesenchymal stem cells: prospects for cancer therapyLong-Jun Dai, Xu-Yong Sun, Garth L. Warnock 13. RNA Interference for Oncology: Clinical Prospects Beyond the HypeEishi Ashihara and Taira Maekawa14. Cell Therapy using Adult Stem Cells in Osteonecrosis and Nonunion FracturesJean-Philippe Hauzeur 15. Stem Cell Therapies for the Treatment of Spinal Cord Injuries: Current Progress in Basic Science and Clinical ResearchHilary North and John Kessler16. Pluripotent Stem Cells for Neural RegenerationSyed Ameer Basha Paspala, Aleem Ahmed Khan, 17. Synovial Mesenchymal Stem Cells and their Applications in Musculoskeletal RegenerationYvonne Peck and Dong-An Wang 18. Stem Cell Therapy Aided liver RegenerationNingning Yang and Manrong Jiang19. Application of Microfluidics of Study Stem Cell DynamicsHuaying Chen and Robert E. Nordon 20. Biomimetic Multiscale Topography for Cell AlignmentKara E. McCloskey 21. Spinal Cord Repair by Means of Tissue Engineered ScaffoldsMindan Wang,  Xiongbiao Chen, and  David J. Schreyer 22. Stem Cells in Ligament Tissue EngineeringMukai Chimutengwende-Gordon and Wasim Khan23. Biomaterials for Bone Tissue EngineeringQizhi Chen 24. Gene Therapy for the Inner Ear: Progress and ProspectsHong Sun, Aji Huang, Hong Liu, and Shousong Cao 25. Preclinical Studies on Growth Plate Cartilage Regeneration Using Chondrocytes or Mesenchymal Stem CellsRosa Chung and Cory J Xian26. Cell and Gene Transfer Strategies for Vascularization During Skin Wound HealingBenoit Hendrickx, Margot Den Hondt, Kristoff Verdonck, Jan J. Vranckx, and Aernout Luttun

Erscheint lt. Verlag 14.6.2013
Zusatzinfo XVII, 705 p. 107 illus., 85 illus. in color.
Verlagsort Totowa
Sprache englisch
Themenwelt Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Technik Umwelttechnik / Biotechnologie
Schlagworte Cell • emerging • Gene • gene therapy • Mahato • Trend
ISBN-10 1-62703-417-X / 162703417X
ISBN-13 978-1-62703-417-3 / 9781627034173
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