The Brugada Syndrome (eBook)

Charles Antzelevitch, PhD, is Executive Director/Director of Research; Gordon K. Moe Scholar; Professor of Pharmacology at the Masonic Medical Research Laboratory; Utica, New York. Pedro Brugada, MD, PhD, is Professor of Cardiology at the Cardiovascular Center OLV Hospital in Aalst, Belgium.

Contributors.

Preface.

Dedication.

1 Brugada Syndrome: Overview.

2 History of the Brugada Syndrome.

3 Biophysical Analysis of Mutant Sodium Channels in Brugada
Syndrome.

4 Molecular Genetics of the Brugada Syndrome.

5 Cellular Mechanisms Underlying the Brugada Syndrome.

6 Brugada Syndrome: Diagnostic Criteria.

7 Value of 12 Lead ECG and Derived Methodologies in the
Diagnosis of Brugada Disease.

8 Brugada Syndrome: Relationship to Other Arrhythmogenic
Syndromes.

9 ST Segment Elevation and Sudden Death in the Athlete.

10 Brugada Syndrome Genetics. Genetic Screening- Role in
Diagnosis.

11 Genotype-Phenotype Relationship in Brugada Syndrome.

12 Gender Differences in Brugada Syndrome.

13 Predisposing Factors.

14 Acquired Forms of Brugada Syndrome.

15 Brugada Syndrome and supraventricular tacharrhythmias.

16 Prognosis in Individuals with the Brugada Syndrome.

17 Treatment of the Brugada Syndrome with the Implantable
Cardioverter Defibrillator.

18 Pharmacologic Approach to Therapy of the Brugada Syndrome:
Quinidine as an Alterative to ICD Therapy?.

19 Potential for Ablation Therapy in Patients with the Brugada
Syndrome.

Index