Markers in Cardiology (eBook)

Jesse E. Adams, MD FACC University of Louisville Division of Cardiology 100 Mallard Creek Louisville, KY 40202 USA Fred Apple, PhD Department of Laboratory Medicine and Pathology Hennepin County Medical Center and University of Minnesota School of Medicine Minneapolis, MN USA Allan S. Jaffe, MD Cardiovascular Division and Cardiovascular Research Institute and Division of Laboratory Medicine Mayo Clinic and Medical School Rochester, Minnesota USA

Markers in Cardiology : A CASE-ORIENTED APPROACH 1
Contents 7
Contributors 9
Preface 11
Part 1 Cardiac troponins 13
1 Basics of cardiac troponin: practical aspects of assays, potential analytical confounders, and clinical interpretation 15
2 Diagnostic use of cardiac troponins in ST-segment elevation myocardial infarction 27
3 Therapeutic implications of cardiac troponins in ST-segment elevation and non-ST-segment elevation myocardial infarction 39
4 Ischemic heart disease in the absence of overt coronary artery disease 63
5 So you think you have a "false positive'' troponin? 71
6 Use of cardiac troponin in patients in non-ischemic pathologies and exposure to environmental toxins 82
7 Cardiac troponins in patients with congestive heart failure 91
8 Troponins and the critically Ill patient 99
9 Cardiac troponins and renal failure 108
10 Cardiac biomarkers: detection of in-hospital myocardial reinfarction 123
Part 2 Natriuretic peptides 129
11 The future: interpreting new guidelines for myocardial infarction 131
12 Basics of natriuretic peptides: practical aspects of assays, potential analytical confounders, and clinical interpretation, 140
13 Natriruetic peptides in clinical practice 146
14 Outpatient evaluation for cardiovascular diseases using natriuretic peptide testing 158
15 Natriuretic peptides in patients with renal failure 182
16 Congestive heart failure: treatment implications of natriuretic peptides 193
17 Utilizing multimarker strategies in patients who present with congestive heart failure 203
Part 3 Contemporary markers of risk 219
18 Clinical integration of C-reactive protein for primary and secondary risk factor stratification 221
19 Lipoprotein subfraction analysis using nuclear magnetic resonance spectroscopy 229
Index 263

"I think this is a good book and good value for money. It is fairly light reading and I found myself wanting to make notes and use it as a point of reference as it pulls things together well. Therefore, I would recommend it to others." (Cardiology News, February 2009)