Thoracic Vein Arrhythmias (eBook)

Mechanisms and Treatment
eBook Download: PDF
2008 | 1. Auflage
368 Seiten
Wiley (Verlag)
978-0-470-75143-5 (ISBN)

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In 1998 Professor Haïssaguerre and his colleagues made the initial observation in patients that triggering foci in or around the pulmonary veins initiate some types of atrial fibrillation. Since then it has become clear that atrial fibrillation and other atrial tachyarrhythmias can be initiated (and possibly maintained) by triggering foci in any of the thoracic veins. This concept is now one of the most current topics in electrophysiology, and while it is a topic of frequent discussion in the major cardiology and electrophysiology journals, Thoracic Vein Arrhythmias: Mechanisms and Treatment is the first state-of-the art multi-authored textbook that integrates the advances made in this rapidly developing new area of cardiac arrhythmias for the global community.

Edited by Drs. Shih-Ann Chen, Michel Haïssaguerre, and Douglas P. Zipes, who are at the forefront of advances in this field of cardiology, and with contributions from authors representing an international array of authorities in their individual fields, this text will be an invaluable reference to students, basic scientists, and clinicians with an interest in any aspect of cardiac arrhythmia.


  • First textbook to provide comprehensive, critical and insightful review by leading experts in the exciting field of thoracic vein arrhythmias.
  • Contains review of the current status of thoracic vein arrhythmias, and speculation on how the new findings will impact on treatment of cardiac arrhythmias.
  • The chapters outline how progress is being made on several fronts ranging from basic mechanisms to invasive treatment for thoracic vein arrhythmias.


Shih-Ann Chen, MD

Cardiology Vetrans General Hospital

201 SEC 2 Shih-Pai Road

Taipei, Taiwan


Michel Haissaguerre, MD

Hospital Cardiologique de Haut-L'Eveque

Ave du Magella

Pessac, France


Douglas P. Zipes

Krannert Institute of Cardiology

Indiannapolis, IN


In 1998 Professor Ha ssaguerre and his colleagues made the initial observation in patients that triggering foci in or around the pulmonary veins initiate some types of atrial fibrillation. Since then it has become clear that atrial fibrillation and other atrial tachyarrhythmias can be initiated (and possibly maintained) by triggering foci in any of the thoracic veins. This concept is now one of the most current topics in electrophysiology, and while it is a topic of frequent discussion in the major cardiology and electrophysiology journals, Thoracic Vein Arrhythmias: Mechanisms and Treatment is the first state-of-the art multi-authored textbook that integrates the advances made in this rapidly developing new area of cardiac arrhythmias for the global community. Edited by Drs. Shih-Ann Chen, Michel Ha ssaguerre, and Douglas P. Zipes, who are at the forefront of advances in this field of cardiology, and with contributions from authors representing an international array of authorities in their individual fields, this text will be an invaluable reference to students, basic scientists, and clinicians with an interest in any aspect of cardiac arrhythmia. First textbook to provide comprehensive, critical and insightful review by leading experts in the exciting field of thoracic vein arrhythmias. Contains review of the current status of thoracic vein arrhythmias, and speculation on how the new findings will impact on treatment of cardiac arrhythmias. The chapters outline how progress is being made on several fronts ranging from basic mechanisms to invasive treatment for thoracic vein arrhythmias.

Shih-Ann Chen, MD, Taipei Veterans General Hospital, Division of Cardiology, Taipei, Taiwan. Michel Haissaguerre, MD, Hospital Cardiologique de Haut-L'Eveque, Pessac, France. Douglas P. Zipes, Krannert Institute of Cardiology, Indianapolis, IN.

Thoracic Vein Arrhythmias 5
Contents 7
Contributors 10
Foreword 15
Preface 17
Part I History of thoracic vein arrhythmias 19
1 History of thoracic vein arrhythmias: pulmonary veins and venae cavae 21
2 The ligament of Marshall 29
3 Coronary sinus electrophysiology and arrhythmogenesis: historical developments 39
Part II Anatomy and basic electrophysiology of the thoracic veins 49
4 Anatomy of the pulmonary veins 51
5 Anatomy of the pulmonary vein–atrium junction 60
6 Anatomy of the vena cava: an electrophysiological perspective 72
7 Anatomy of the coronary sinus 84
8 Imaging of the cardiac and thoracic veins 95
9 Immunohistology of the thoracic veins 117
10 Ionic currents and mechanisms of ectopy from the thoracic veins 129
11 Stretch-related atrial remodeling: role in the genesis of atrial fibrillation 139
12 High-density mapping of thoracic vein arrhythmias 153
13 Optical mapping of thoracic vein arrhythmias 166
14 Effects of electrical stimulation of autonomic ganglia at the thoracic veins 175
15 Maintenance of atrial fibrillation: thoracic vein or atrial substrate? 185
Part III Clinical electrophysiology and ablation therapy of thoracic vein atrial fibrillation 201
16 Electrocardiographic characteristics of atrial fibrillation initiators from the thoracic veins 203
17 Mapping of atrial fibrillation initiators from the thoracic veins 214
18 Autonomic modulation of thoracic vein atrial fibrillation 229
19 Clinical electrophysiology of the pulmonary veins 235
20 Catheter ablation of pulmonary vein atrial fibrillation: circumferential ablation 247
21 Catheter ablation of pulmonary vein atrial fibrillation: electrophysiologically guided procedure 266
22 Clinical electrophysiology and catheter ablation of atrial fibrillation from the superior vena cava 281
23 Clinical electrophysiology and catheter ablation of atrial fibrillation from the ligament of Marshall 294
24 Clinical electrophysiology and catheter ablation of the coronary sinus in patients with atrial fibrillation 303
25 Pulmonary vein isolation for treatment of atrial fibrillation in patients with structural heart disease 313
26 Role of linear ablation in thoracic vein atrial fibrillation 327
27 New technologies for catheter isolation of the pulmonary veins 342
28 Surgical ablation of atrial fibrillation: pulmonary vein isolation 354
Index 362

DOODY'S NOTES (Nov 2004?)

Sammy Khatib, MD(Ochsner Clinic Foundation)

Weighted Numerical Score: 94 - 4 Stars!

"The strength of this book lies in the presentation of the
information. The authors first provide the background basic science
including the mechanisms involved and follow this with clinical
information."

"The field of thoracic veins and their ability to initiate
and/or sustain atrial fibrillation is exciting and rapidly
evolving. The authors have done an outstanding job in the first
text of its kind. This is a comprehensive review of the subject
which identifies areas which need further research. This is without
doubt the definitive text on thoracic vein arrhythmias to date and
is a must-read for anyone interested in the field of cardiac
electrophysiology."

Erscheint lt. Verlag 15.4.2008
Sprache englisch
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Schlagworte electrophysiology • Elektrophysiologie • Medical Science • Medizin
ISBN-10 0-470-75143-6 / 0470751436
ISBN-13 978-0-470-75143-5 / 9780470751435
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