Manual of Hypertension of the European Society of Hypertension

Background, History and Epidemiology


Epidemiology of Hypertension; Renata Cífková


The Total Cardiovascular Risk; Claudio Borghi, Arrigo Francesco Giuseppe Cicero, and Ettore Ambrosioni


Associated Risk Factors


Classical and New Risk Factors; Manolis S. Kallistratos and Athanasios J. Manolis


Pulse Pressure as a Cardiovascular Risk Factor; Athanase Benetos


Clinical Significance of High Heart Rate in Hypertension; Paolo Palatini and Guido Grassi


Obesity and Obstructive Sleep Apnea; Marzena Chrostowska, Anna Szyndler, Jacek Wolf, and Krzysztof Narkiewicz


Diabetes Mellitus; Peter M. Nilsson


Stress, Psychosocial, and Other Risk Factors in the Hypertensive Patient; Philippe Van De Borne


Blood Pressure Variability: Methodological Aspects, Pathophysiological and Clinical Implications; Gianfranco Parati, Juan Eugenio Ochoa, and Grzegorz Bilo


Antihypertensive Treatment Strategies; Giuseppe Mancia


Ethiological and Pathophysiological Aspects


Hemodynamics of Hypertension; Per Omvik and Per Lund-Johansen


Genetic Basis of Blood Pressure and Hypertension; Sandosh Padmanabhan, Mark Caulfield, and Anna F. Dominiczak


Structural Cardiovascular Changes in Hypertension; Harry A.J. Struijker-Boudier


Impaired Autonomic Cardiovascular Control in Hypertension; Guido Grassi, Gianmaria Brambilla, and Gino Seravalle


The Renin–Angiotensin–Aldosterone System; Ulrike M. Steckelings and Thomas Unger


Etiological and Pathophysiological Aspects of Hypertension: Other Humoral–Endocrine Factors; Michel Burnier


Target Organ Damage: Measurements/Clinical Importance


Cardiac Damage and Progression to Heart Failure; E. Agabiti Rosei, M.L Muiesan, and R.E. Schmieder


Brain Damage; Cristina Sierra and Antonio Coca


Large Artery Damage: Measurement and Clinical Importance; Stéphane Laurent, and Michel E Safar


Small Artery Structure and Function in Hypertension; Anthony M. Heagerty, Sarah B. Withers, Ashley S. Izzard,


Adam S. Greenstein, and Reza Aghamohammadzadeh


Endothelial Damage: Measurement and Clinical Importance; Lorenzo Ghiadoni, Agostino Virdis, and Stefano Taddei


Renal Damage and Hypertension: Mechanisms of Renal End-Organ Damage; Hermann Haller


Retinal Changes in Hypertension; Martin Ritt, Enrico Agabiti-Rosei, and Roland E Schmieder


BP Measurements and Other Diagnostic Procedures


BP Measurements and Other Diagnostic Procedures; Jean-Philippe Baguet, Jean-Michel Mallion, and Denis L. Clement


Blood Pressure Response to Acute Physical and Mental Stress; Robert Fagard and Guido Grassi


Central Blood Pressure; Cristina Giannattasio and Stéphane Laurent


The Diagnostic Approach in Uncomplicated and Complicated Hypertension; Athanasios J. Manolis and Costas Tsioufis


Therapeutic Aspects


Blood Pressure Targets of Antihypertensive Treatment; Giuseppe Mancia and Guido Grassi


Interventional Trials in Hypertension: What Have We Learned and What Remains to be Learned? Alberto Zanchetti


The Nephroprotective Effect of Antihypertensive Treatment; Luis M. Ruilope and Julian Segura


Nonpharmacological Interventions; Stefan Engeli and Jens Jordan


Medical Treatment of Hypertension: Monotherapy and Combination Therapy; M. Burnier, G. Wuerzner and B. Waeber


Emerging Antihypertensive Drugs; Massimo Volpe and Giuliano Tocci


The Polypill; Marie Briet and Michel Azizi


Invasive Procedures; Roland E. Schmieder


Special Conditions


Clinical Management of Patients Presenting with Hypertension and Peripheral Artery Disease; Denis L. Clement


Resistant and Malignant Hypertension; Josep Redon, Fernando Martinez, and Gernot Pichtler


Hypertensive Emergencies and Urgencies; Cesare Cuspidi and Achille C. Pessina


Secondary Hypertension: Diagnosis and Treatment; Peter W De Leeuw


Hypertension in Diabetes Mellitus; Peter M. Nilsson


Hypertension in Children and Adolescents; Empar Lurbe


Hypertension in Pregnancy; Renata Cífková


Posttransplant Hypertension; Martin Hausberg and Karl Heinz Rahn


Hypertension in Patients with Renal Parenchymal Disease, Chronic Renal Failure, and Chronic Dialysis; Jose L. Rodicio and Jose A. García-Donaire


The Metabolic Syndrome in Hypertension; Josep Redon, Fernando Martinez and Maria Jose Fabia


White-Coat and Masked Hypertension; Robert Fagard


Secondary Prevention of Stroke; Miguel Camafort, Monica Doménech and Antonio Coca


Hypertension and Atrial Fibrillation: Modern Epidemiologic, Pathophysiologic, and Therapeutic Aspects; Athanasios J. Manolis, L.E. Poulimenos, J Kostis


Management of Perioperative Hypertension; Paul E. Marik


Economic and Organizational Issues


Pharmacoeconomic and Cost–Benefit Aspects; Ettore Ambrosioni and Claudio Borghi


How to Organize and Run a Hypertension Center; Csaba Farsang and Margus Viigimaa


Current Problems


Blood Pressure Control in Europe; Bernard Waeber, François Feihl and Giuseppe Mancia


Hypertension in the Very Elderly; Nigel S. Beckett


Hypertension in Acute Stroke; Terence J. Quinn, John A. Goodfellow and John L. Reid


Cardiovascular Risk of Nonsteroidal Anti-Inflammatory Drugs; Csaba Farsang


Compliance to Treatment in Hypertension; Serap Erdine and Margus Viigimaa


Antihypertensive Treatment in Patients with Heart Failure; Nisha B. Mistry, Sverre E. Kjeldsen, and Arne S. Westheim


Residual Risk and Resistance to the Benefits of Antihypertensive Treatment; Alberto Zanchetti


Index