Clinical Pharmacology and Therapeutics (eBook)

Gerard A. McKay: Consultant Physician and Honorary ClinicalSenior Lecturer, Glasgow Royal Infirmary John L. Reid: Emeritus Professor of Medicine andTherapeutics, University of Glasgow Matthew R. Walters: Professor of Clinical Pharmacologyand Honorary Consultant Physician, Division of Cardiovascular andMedical Sciences, University of Glasgow

Contributors, iv

Preface, vi

Acknowledgements, vii

Part 1 Principles of Clinical Pharmacology

1 Pharmacodynamics and pharmacokinetics, 3

2 Clinical trials and drug development, 12

Part 2 Aspects of Therapeutics

3 Drugs and gastrointestinal disease, 21

4 Management of coronary artery disease and its complications,33

5 Primary and secondary prevention of cardiovascular disease,58

6 Drugs used to treat respiratory disease, 78

7 Drugs used to treat neurological disease, 89

8 Treatment of psychiatric disorders, 108

9 Antimicrobial therapy, 124

10 HIV and antiretroviral treatment, 148

11 Travel medicine and tropical disease, 160

12 Drugs and endocrine disease, 171

13 Drugs and the reproductive system, 190

14 Drugs and the urological system, 199

15 Cancer therapeutics, 205

16 Immunopharmacology, 217

17 Corticosteroids, 225

18 Drugs and the blood including anticoagulants and thrombolyticdrugs, 229

19 Drugs and inflammatory joint disease, 244

20 Anaesthesia and the relief of pain, 254

Part 3 Practical Aspects of Prescribing

21 Clinical pharmacokinetics: dosage individualisation, 267

22 Influence of renal and hepatic disease on pharmacokineticsand pharmacodynamics, 273

23 Prescribing at extremes of age, 278

24 Drugs in pregnant and breastfeeding women, 282

25 Pharmacoeconomics: the economic evaluation of new drugs,290

26 Poisoning and drug overdose, 297

27 Drugs you may need in a hurry, 313

28 Prescribing and its pitfalls, 318

Index, 326

"The popularity of this Lecture Notes book merits an 8thedition publication." (British Journal Global &Travel Health, 1 August 2013)

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