Immunodominance (eBook)

Jeffrey A. Frelinger received his Ph.D. in immunology at the California Institute of Technology, Pasadena in 1973 and worked as a post-doc at the University of Michigan Medical School, Ann Arbor. Since 1988 he is professor and chair at the Department of Microbiology and Immunology and Associate Director for Research at the Center for Infectious Disease at the University of North Carolina, School of Medicine, Chapel Hill, USA. His major research interests are immunogenetics, molecular immunology and cellular immunology.

MECHANICS OF ANTIGEN PROCESSING
Class I (Rock, USA; Neefjes, Netherlands)
Class II (Unanue, USA)
Impact of MHC on epitope selection (Sette, USA)
PROTEOSOME SPECIFICITY AND IMMUNO-PROTEOSOMES
DRIPS (Yewdell, Bennick, USA)
Classical processing (Cresswell, USA)
EFFECT OF THE T CELL REPERTOIRE ON DOMINANCE
Innate repertoire (Rocha, France)
Selected repertoire (Sherman, USA)
Thymic Development (Zuniga, Pflucker, Canada; Robey, USA; Fowlkes, USA)
Regulatory T cells (Paul, USA; O'Garra, UK)
EFFECTS OF PATHOGENS ON THE IMMUNE RESPONSE
Herpes viruses (Rickenson, UK; Moss, Australia; Hill, USA)
HIV (McMichael, UK; Gotch, UK; Tackiguchi; Japan)
Influenza (Doherty, Austalia; Braciale, US)
Listeria (Harty, USA; Pamer, USA)
TB/Leprosy (Flynn, USA; Bloom, USA)
Malaria (Hill, UK; Nussenswieg, USA)
Generation of Memory T cells (Woodland, USA; Heath, Australia)
HTLV (Bangham, UK)
Hepatitis (Chisari, USA)

"...a timely book in a fast-moving field."
ChemMedChem

"Die Immunologie ist nach wie vor und mehr denn je ein spannendes Thema und die genauere Kenntnis der Immundominanz liefert zum einen einen weiteren Baustein zum besseren Verständnis der Mechanismen, könnte aber auch bei der Entwicklung besserer und sichererer Antigene für Impfungen helfen."
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