New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity

Problems and Prospects of Discovering New Drugs from Higher Plants by Pharmacological Screening.- A. Introduction.- B. Value of Drugs Obtained from Higher Plants.- C. Apathy in Plant-Derived Drug Development.- D. Current Level of Worldwide Research on Plant-Derived Drugs.- E. Pharmacological Screening Programs for Plant Extracts.- F. Problems in the Pharmacological Screening of Extracts from Higher Plants.- G. Prospects for the Future.- References.- Pharmacological Approaches to Natural Product Screening and Evaluation.- A. Ideal Requirements for a Primary Screen.- B. Past Approaches to Primary Pharmacological Screening.- C. Multidimensional Primary Screening.- D. Multidimensional Secondary Screening of Extracts and Pure Compounds.- E. Tertiary Evaluation.- F. Addendum-Sample Print-Out of Computerized Hippocratic Evaluation.- References.- Recent Experimental and Clinical Data Concerning Antitumor and Cytotoxic Agents from Plants.- A. Introduction.- B. Terpenoids.- C. Miscellaneous Compounds.- D. Alkaloids.- E. Summary.- References.- Recent Advances in the Field of Antibiotics.- A. Introduction.- B. Acetate/Propionate-Derived Metabolites.- C. Isoprenoid Metabolites.- D. Amino Acid-Derived Metabolites.- E. Conclusion.- References.- Progress in the Chemistry of Alkaloids with Pharmacological or Biological Activity.- References.- Plant Mono-, Di- and Sesquiterpenoids with Pharmacological or Therapeutical Activity.- A. Introduction.- B. Classification.- C. General Biological Properties.- D. Monoterpenes.- E. Sesquiterpenes and Diterpenes.- F. Conclusion.- References.- Saponins with Biological and Pharmacological Activity.- A. Introduction.- B. Saponins of Licorice.- C. The Saponins of Bupleuri Radix and Platycodi Radix.- D. Saponins of Polygalae Radix and Senegae Radix.- E.Saponins of Akebiae Vitis.- F. Aescin, the Saponins of the Seeds of Aesculus hippocastanum.- G. Saponins of Ginseng.- H. Saponins of Zizyphus Spinosi Semen.- I. Concluding Remarks.- References.- Dimeric Natural Compounds with Pharmacological Activity.- A. Definitions and Classification.- B. The Formation of Dimeric Compounds.- C. Pharmacological and Physiological Activity.- References.- Chemical and Biological Investigations on Indian Medicinal Plants.- A. Introduction.- B. Alkaloids.- C. Oxygen Heterocycles.- D. Terpenoids.- E. Glycosides.- F. Miscellaneous.- References.- Chemistry of Neolignans with Potential Biological Activity.- A. Introduction.- B. Benzofuranoid Neolignans.- C. Benzodioxane and Other Neolignans.- D. Bicyclo [3, 2, 1] octanoid Neolignans.- E. Biogenesis of Neolignans.- F. Conclusion.- References.- Natural Substances with Effects on the Liver.- References.- The Modification of Natural Substances in the Modern Drug Synthesis.- A. Introduction.- B. Main Part.- References.