Basics of PET Imaging (eBook)

Preface
Chapter 1
Radioactive Decay and Interaction of Radiation with Matter Atomic Structure
Radioactive Decay
General Radioactive Decay Equations
Successive Decay Equations
Units of Radioactivity
Units of Radioactivity in System Internationale
Calculation
Interaction of Radiation with Matter
Interaction of Charged Particles with Matter
Interaction of ( Radiation with Matter
Attenuation of ( Radiations
Questions
References and Suggested Reading
Chapter 2
PET Scanning Systems Background
Solid Detectors in PET
Photomultiplier Tube
Pulse Height Analyzer
Arrangement of Detectors
PET Scanners
Hybrid Scintillation Cameras
PET/CT Scanners
Small Animal PET Scanner
Mobile PET
Questions
References and Suggested Reading
Chapter 3
Data Acquisition and Corrections Data Acquisition
Two-dimensional versus three-dimensional
PET/CT data acquisition
Factors Affecting Acquired Data
Normalization
Photon Attenuation
Random Coincidences
Scatter Coincidences
Dead Time
Radial Elongation
Questions
Suggested Reading
Chapter 4
Image Reconstruction, Storage and Display Simple Backprojection
Filtered Backprojection
The Convolution Method
The Fourier Method
Types of Filters
Iterative Reconstruction
3-D Reconstruction
Partial Volume Effect
Storage
Display
Software and DICOM
PACS
Teleradiology
Questions
Referencesand Suggested Reading
Chapter 5
Performance Characteristics of PET Scanners Spatial Resolution
Sensitivity
Noise
Scatter Fraction
Contrast
Quality Control of PET Scanners
Daily Quality Control Tests
Weekly Quality Control Tests
Acceptance Tests
Spatial Resolution
Sensitivity
Scatter Fraction
Count Rate Losses and Random Coincidences
Questions
References and Suggested Reading Chapter 6
Cyclotron and Production of PET Radionuclides Cyclotron Operation
Target and its Processing
Equation for Production of Radionuclides
Specific Activity
Production of Short-lived Positron-emitters
Fluorine-18
Carbon-11
Nitrogen-13
Oxygen-15
Iodine-124
Strontium-82
Technetium-94m
Questions
Suggested Reading
Chapter 7
Synthesis of PET Radiopharmaceuticals PET Radiopharmaceuticals
18F-Sodium Fluoride
18F-Fluorodeoxyglucose (FDG)
6-18F-L-Fluorodopa
18F-Fluorothymidine (FLT)
15O-Water
n-15O-Butanol
13N-Ammonia
11C-Sodium Acetate
11C-Flumazenil
11C-Methylspiperone (MSP)
11C-L-Methonine
11C-Raclopride
82Rb-Rubidium Chloride
Automated Synthesis Devices
Quality Control of PET Radiopharmaceuticals
Specifications for Routine PET Radiopharmaceuticals
18F-FDG
6-18F-L-Fluorodopa
13N-Ammonia
Questions
References and Suggested Reading
Chapter 8