Signaling in the Heart (eBook)
XX, 507 Seiten
Springer US (Verlag)
978-1-4419-9461-5 (ISBN)
Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact.
This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
Preface Part I Methodologies 1. Tools to study signaling Part II Normal Signaling Processes 2. Cell-cycle Signaling, Epigenetic and Nuclear Function 3. Signaling in the Endothelium 4. Rapid Signaling Pathways 5. Growth Factors Signaling Pathways 6. Ion Channels Signaling 7. Lipids Signaling Part III Mitochondria 8. Heart Mitochondria: A Receiver and Integrator of Signals Part IV Pediatric Cardiology 9. Signaling Pathways in Cardiovascular Development 10. Signaling in Congenital Heart Disease Part V Aging 11. Signaling in the Aging Heart Part VI Signaling in Cardiovascular Disease 12. Signaling in Endomyocarditis. 13. Signaling Pathways in Hypertension 14. Gene Expression and Signaling Pathways in Myocardial Ischemia 15. Signaling in Hypertrophy and Heart Failure 16. Signaling in Diabetes and Metabolic Syndrome 17. Dysrhythmias/Channelopathies and Signaling Pathways 18. Signaling in Atherosclerosis Part VII Targeting Signaling in Cardiovascular Medicine. 19. Stem Cells Signaling Pathways 20. Cardioprotection and Signaling Pathways 21. Targeting Specific Pathways Part VIII Looking to the Future 22. Future Frontiers in Cardiovascular Signaling. Glossary
| Erscheint lt. Verlag | 21.6.2011 |
|---|---|
| Zusatzinfo | XX, 507 p. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie | |
| Schlagworte | Cardiovascular • myocardium • Pathways • Signaling • Vasculature |
| ISBN-10 | 1-4419-9461-0 / 1441994610 |
| ISBN-13 | 978-1-4419-9461-5 / 9781441994615 |
| Haben Sie eine Frage zum Produkt? |
PDF (Wasserzeichen)Größe: 17,0 MB
DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich
