Antithrombotic Drug Therapy in Cardiovascular Disease (eBook)
XIII, 475 Seiten
Humana Press (Verlag)
978-1-60327-235-3 (ISBN)
Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis plays an essential role in the pathogenesis of acute coronary syndromes (ACS), ischemic complications of percutaneous coronary intervention (PCI), venous thromboembolic disease, and embolic complications of arrhythmias and various cardiomyopathies.
Written by experts in the field, Antithrombotic Drug Therapy in Cardiovascular Disease carefully examines individual and various combinations of the available antithrombotic regimens including fibrinolytic agents, antiplatelet therapies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticoagulant therapies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and synthetic factor X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). A detailed overview, Antithrombotic Drug Therapy in Cardiovascular Disease presents the evidence demonstrating the efficacy of available antithrombotic therapies in specific disease states such as atrial fibrillation, cardiomyopathy, valvular heart disease, and heparin-induced thrombocytopenia (HIT).
Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis plays an essential role in the pathogenesis of acute coronary syndromes (ACS), ischemic complications of percutaneous coronary intervention (PCI), venous thromboembolic disease, and embolic complications of arrhythmias and various cardiomyopathies.Written by experts in the field, Antithrombotic Drug Therapy in Cardiovascular Disease carefully examines individual and various combinations of the available antithrombotic regimens including fibrinolytic agents, antiplatelet therapies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticoagulant therapies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and synthetic factor X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). A detailed overview, Antithrombotic Drug Therapy in Cardiovascular Disease presents the evidence demonstrating the efficacy of available antithrombotic therapies in specific disease states such as atrial fibrillation, cardiomyopathy, valvular heart disease, and heparin-induced thrombocytopenia (HIT).
Preface 6
Contents 8
Contributors 10
Basic Principles 13
Platelets in Arterial Thrombosis 14
The Role of Coagulation in Arterial and Venous Thrombosis 29
The Link Between Inflammation and Thrombosis 49
The Genetics of Thrombosis 72
Antithrombotic Therapy for Stable Coronary Atherosclerotic Disease 124
Aspirin in Primary and Secondary Prevention of Cardiovascular Disease 125
Thienopyridines in Stable Coronary Disease 138
Antithrombotic Therapy for NSTE ACS 149
Antiplatelet Therapies in Unstable Angina and Non-ST Segment Elevation Myocardial Infarction 150
Unfractionated Heparin and Enoxaparin for the Management of Non- ST- Segment Elevation Acute Coronary Syndromes 169
Direct Thrombin Inhibitors in Acute Coronary Syndromes 186
Synthetic Factor Xa Inhibition in Acute Coronary Syndromes 205
Antithrombotic Therapy for STEMI 218
Antiplatelet Therapies: Aspirin, Clopidogrel and Thienopyridines, and Glycoprotein IIb/ IIIa Inhibitors for the Management of ST- Segment Elevation Myocardial Infarction 219
Antithrombin Therapy for Acute ST-Segment Elevation Myocardial Infarction 234
Fibrinolysis and Facilitated PCI 246
Antithrombotic Therapy in Interventional Cardiology 257
Antithrombotic Therapy in Percutaneous Coronary Intervention 258
Antithrombotic Therapy in Carotid and Peripheral Intervention 280
Monitoring of Antithrombotic Therapies in Interventional Cardiology 303
Antithrombotic Therapy in Venous Thromboembolism 325
Venous Thromboembolism 326
Fibrinolysis for Pulmonary Embolism 346
Duration of Anticoagulant Therapy After Venous Thromboembolism 357
Clinical Consideration 380
Antithrombotic Therapy for Atrial Fibrillation and Cardioversion 381
Antithrombotic Therapy for Valvular Heart Disease 396
Antithrombotic Therapy in Heart Failure and Cardiomyopathy 415
Heparin-Induced Thrombocytopenia 424
Resistance to Antiplatelet Drugs 437
Index 453
| Erscheint lt. Verlag | 20.3.2010 |
|---|---|
| Reihe/Serie | Contemporary Cardiology | Contemporary Cardiology |
| Zusatzinfo | XIII, 475 p. |
| Verlagsort | Totowa |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie |
| Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie | |
| Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie | |
| Schlagworte | Antiplatelet therapies • Antithrombotic therapies • Atrial Fibrillation • Cardiovascular • Deep vein thrombosis • Myocardial Infarction • Pulmonary embolism • thrombosis • Unstable angina |
| ISBN-10 | 1-60327-235-6 / 1603272356 |
| ISBN-13 | 978-1-60327-235-3 / 9781603272353 |
| Haben Sie eine Frage zum Produkt? |
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