Cardiovascular Research -

Cardiovascular Research (eBook)

New Technologies, Methods, and Applications
eBook Download: PDF
2007 | 2006
XV, 239 Seiten
Springer US (Verlag)
978-0-387-23329-1 (ISBN)
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In the last decade, technical improvements have changed the inventory of many research laboratories. New techniques and discoveries continuously give rise to observations that result in the de?nition of new research objectives. In the past, - search departments were clearly demarcated. Nowadays, technology that is shared by all lines of research stimulates convergence of research interests. This also - plies to cardiovascular research. Vascular occlusive disease is now core business for researchers employed by cardiology, vascular surgery, vascular medicine, - diology, cell biology, chemistry, physiology, and many other areas. Knowledge on actual research development is shared by researchers with different skills. It is sometimes dif?cult to acquire expertise when a researcher feels his experimental work could be improved by introducing a new research technique. In this book, the investigator will ?nd an overview of recent developments that are relevant for research in general but cardiovascular research in particular. Genomics, p- teomics, microarray, RNAi, stem cells, and progenitor cells are just some phrases that have become increasingly prevalent in literature in the last few years and that are recognized by many, but are fully understood by few. In this book, experts share the most appreciated new developments and techniques in cardiovascular research. We hope that this book will help the reader who is working in the ?eld of cardiovascular research to understand and critically appreciate current research, and that it will help improve the quality of experimental work. Dr G.
In the last decade, technical improvements have changed the inventory of many research laboratories. New techniques and discoveries continuously give rise to observations that result in the de?nition of new research objectives. In the past, - search departments were clearly demarcated. Nowadays, technology that is shared by all lines of research stimulates convergence of research interests. This also - plies to cardiovascular research. Vascular occlusive disease is now core business for researchers employed by cardiology, vascular surgery, vascular medicine, - diology, cell biology, chemistry, physiology, and many other areas. Knowledge on actual research development is shared by researchers with different skills. It is sometimes dif?cult to acquire expertise when a researcher feels his experimental work could be improved by introducing a new research technique. In this book, the investigator will ?nd an overview of recent developments that are relevant for research in general but cardiovascular research in particular. Genomics, p- teomics, microarray, RNAi, stem cells, and progenitor cells are just some phrases that have become increasingly prevalent in literature in the last few years and that are recognized by many, but are fully understood by few. In this book, experts share the most appreciated new developments and techniques in cardiovascular research. We hope that this book will help the reader who is working in the ?eld of cardiovascular research to understand and critically appreciate current research, and that it will help improve the quality of experimental work. Dr G.

List of Contributors 5
Preface 8
Contents 9
I Methods 30
1 Expression Profiling in Cardiovascular Disease Using Microarrays 31
2 Proteomics: State of the Art and Its Relevance for Gene Therapy 73
3 Cardiovascular Proteomics 93
4 Quantitative Real-Time PCR 103
5 New Technologies in Cardiovascular Research 112
6 The Role of Bioinformatics in Genomic Medicine 129
7 RNA Interference 146
II Applications 156
8 Stem Cells and Cardiomyocytes 157
9 Can Somatic Stem Cells Regenerate Myocardial Tissue? 180
10 Gene Therapy for Angiogenesis 194
11 Tissue Engineering 229
12 Visualization of the Vulnerable Plaque 243
Index 257

Erscheint lt. Verlag 10.6.2007
Zusatzinfo XV, 239 p.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Chirurgie
Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Schlagworte angiogenesis • Cardiology • Cardiovascular • Cell Biology • Development • gene therapy • Physiology • Stem Cells • Surgery • vascular disease
ISBN-10 0-387-23329-6 / 0387233296
ISBN-13 978-0-387-23329-1 / 9780387233291
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