Tietz Textbook of Clinical Chemistry and Molecular Diagnostics

Section I: Principles of Laboratory Medicine * Introduction to Laboratory Medicine * Selection and Analytical Evaluation of Methods - With Statistical Techniques * Clinical Evaluation of Methods * Evidence Based Laboratory Medicine * Establishment and Use of Reference Values * Preanalytical Variables and Biological Variation * Specimen Collection and Processing * Quality Management Section II: Analytical Techniques and Instrumentation * Principles of Basic Techniques and Laboratory Safety * Optical Techniques * Electrochemistry and Chemical Sensors * Electrophoresis * Chromatography and Extraction * Mass Spectrometry * Enzyme and Rate Analyses * Principles of Immunochemical Techniques * Nucleic Acid Techniques * Microfabrication and Microfluidics and Their Application to Clinical Diagnostics * Automation in the Clinical Laboratory * Point-of-Care Testing Section III: Analytes * Amino Acids, Peptides, and Proteins * Serum Enzymes * Enzymes of the Red Blood Cell * Tumor Markers * Kidney Function Tests * Carbohydrates * Lipids, Lipoproteins, Apolipoproteins, and Other Cardiovascular Risk Factors * Electrolytes and Blood Gases * Hormones * Catecholamines and Serotonin * Vitamins and Trace Elements * Hemoglobin, Iron, and Bilirubin * The Porphyrias and Other Disorders of Porphyrin Metabolism * Therapeutic Drugs and Their Management * Clinical Toxicology * Toxic Metals Section IV: Molecular Diagnostics and Genetics * Principles of Molecular Biology * Genomes and Nucleic Acid Alterations * Nucleic Acid Isolation * Inherited Diseases * Identity Assessment * Molecular Methods in Diagnosis and Monitoring of Infectious Diseases * Pharmacogenetics * Hematopoietic Malignancies * Plasma Nucleic Acids Section V: Pathophysiology * Diabetes Mellitus * Cardiovascular Disease * Kidney Disease * Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism * Liver Disease * Gastrointestinal and Pancreatic Diseases * Disorders of Bone and Mineral Metabolism * Pituitary Function and Pathophysiology * The Adrenal Cortex * The Thyroid: Pathophysiology and Thyroid Function Testing * Reproductive Endocrinology and Related Disorders * Pregnancy and its Disorders * Newborn Screening and Inborn Errors of Metabolism * Hemostasis Section VI: Appendix * Reference Information for the Clinical Laboratory