Holland-Frei Cancer Medicine
PMPH-USA Limited (Verlag)
978-1-60795-014-1 (ISBN)
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The consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists and others who treat cancer patients, Cancer Medicine 8 covers the ever-widening sphere of current cancer knowledge and clinical practice. In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology, imaging and therapy. The book is a testament to the editorial panel's creed that innovative, comprehensive, multidisciplinary treatment of cancer patients must be grounded in a fundamental understanding of cancer biology. Cancer Medicine 8 does a superb job of bringing scientific principles into clinical practice. This text is the ultimate resource of new information providing the basis for better informed cancer therapy choices. Cancer Medicine 8 features hundreds of 4-color illustrations, photographs, tables, graphs and algorithms that make this text an invaluable clinical tool in recognizing characteristic appearances of both patient and tissue.
The 137 tightly focused chapters are organized into 5 sections: I: Cardinal Manifestations of Cancer II: Scientific Foundations of Cancer III: Principles of Cancer Diagnosis IV: Principles of Therapeutic Modalities V: Principles of Multidisciplinary Management Major Revisions: Chapter 6: Oncogenes An entire section is devoted to oncogenes like kit, Ret, Braf, Akt genes and the new drugs that specifically target them. This chapter not only provides a list of these new therapies but also insight as to how they target the oncogenes and their mutations, as well as therapy response and efficacy. Chapter 11: Tumor Angiogenesis This chapter provides a wealth of new data and understanding of the mechanisms of angiogenesis and how it contributes to the malignancy of various cancers The Clinical Advancement section provides an extensive summary of new trials investigating numerous novel angiogenesis agents Chapter 33: Chemoprevention This chapter also provides a considerable amount of new information for a broad range of clinical trials such as the HPV vaccine trial Future, Select, Star, Approve and PreSAP.
The rationales for these trials are discussed and resulting data from the completed trials are presented. Chapter 55: Cytokines Research on cytokines is another area that is exploding in magnitude. This chapter presents a wealth of new information on promising new therapeutic agents.There is also updated information on the therapeutic usage of currently available agents such as hemotopoietic growth factors (HGF), erythropoietin and thromobopoietic agents. Chapter 56: Monoclonal Serotherapy A considerable amount of research has been done in the past few years on therapeutic and targeted agents in cancer therapy. Updated information and data is provided from recent trials for therapies previously discussed in Cancer Medicine edition 7 covering therapeutic agents and targeted toxins. Chapter 77: Neoplasms of the Head and Neck There is a discussion of changes in treatment methods for certain cancers such as the recent shift from surgery to combined chemotherapy with radiotherapy for tonsillar cancer, nasal and paranasal sinuses cancers and laryngeal cancer.
Chapter 78: Lung Cancer Advances in diagnostic techniques are described such as ultrasound-guided fine needle aspiration or electromagnetic navigation diagnostic bronchoscopy. Video assisted thoracoscopic surgery (VATS) discussion is updated. New sections are devoted to prognostic and predictive biomarkers.
Waun Ki Hong, MD Division Head Thoracic Head & Neck Medical Oncology, MD Anderson Cancer Center Donald W. Kufe, MDProfessor of MedicineDana Farber Cancer InstituteHarvard Medical School Robert C. Bast Jr, MDVice President for Translation ResearchMD Anderson Cancer Center William Hait, MD, PhDSenior VP and Worldwide Head Ortho Biotech Oncology Research & Development (ORD), Johnson & Johnson Pharmceutical Research & Development Raphael E. Pollock, MD, PhDHead of the Division of Surgery, Professor and Chairman of the Department of Surgical Oncology, Senator A. M. Aiken, Jr. Distinguished Chair M. D. Anderson Cancer Center Ralph R. Weichselbaum, MDDaniel K. Ludwig ProfessorChair Dept of Radiology and Cellular OncologyUniversity of Chicago HospitalDirector Chicago Tumor Institute James F. Holland, MD, ScD (hc)Director Emeritus, Derald H. Ruttenberg Cancer CenterMount Sinai School of Medicine Emil Frei, III, MDPhysician in Chief EmeritusDana Farber Cancer Institute
PART I: CARDINAL MANIFESTATIONS OF CANCER 1: Cardinal Manifestations of Cancer James F. Holland, Emil Frei, III, Waun Ki Hong, Donald Kufe, Robert Bast, William Hait, Raphael Pollock, Ralph Weichselbaum PART II: SCIENTIFIC FOUNDATIONS OF CANCER SECTION 1: CANCER BIOLOGY 2: Molecular Biology, Genomics, and Proteomic, and Mouse Models of Human Cancer Kornelia Polyak, Matthew Meyerson, William Hahn, David Tuveson 3: Cell Proliferation and Differentiation Michael Andreeff, David W. Goodrich, H. Phillip Koeffler 4: Apoptosis and Cancer John Reed 5: Growth Factors and Signal Transduction in Cancer Stuart A. Aaronson, Luca Grumolato 6: Oncogenes Marco A. Pierotti, Milo Frattini, Gabriella Sozzi, Carlo M. Croce 7: Tumor Supressor Genes Gen-Ho Park, Bert Vogelstein, David Cosgrove 8: Genomic Alterations and Chromosomal Abberations in Human Cancer Jeff Trent, Kevin M. Brown, Jonathan J. Keats, Aleksandar Sekulic, Cheryl L. Willman 9: Biochemistry of Cancer Raymond W. Ruddon, Donald W. Kufe 10: Invasion and Metastases Elise C. Kohn 11: Tumor Angiogenesis John Heymach, Judah Folkman, Raghu Kalluri 12: Epigenetics (to include Novel Treatment) Steve Baylin SECTION 2: CANCER IMMUNOLOGY 13: Cancer Immunotherapy Karl S Peggs, Sergio A Quezada, Padmanee Sharma, James P Allison SECTION 3: CANCER ETIOLOGY 14: Genetic Predisposition to Cancer Henry T. Lynch, Vadana Gupta, Marcia S. Brose 15: Chemical Carcinogenesis Ainsley Weston, Curtis C. Harris 16: Hormones and the Etiology of CancerLeslie Bernstein, C. Leigh Pearce, Iona Cheng, Katherine DeLellis Henderson 17: Ionizing Radiation David J. Grdina 18: Ultraviolet Radiation CarcinogenesisJames E. Cleaver, David L. Mitchell 19: Inflammation, Trauma and Physical Agents in Cancer Debbie Laskin 20: RNA Tumor Viruses, Robert Gallo, Marvin S. Reitz 21: Herpesviruses Jeffrey I. Cohen 22: Papillomaviruses and Cervical Neoplasia Christopher P. Crum, Catherine McLachlin 23: Hepatitis Viruses Max W. Sung, Swan N. Thung 24: Parasites Piero Mustacchi SECTION 4: TRANSLATIONAL CANCER MEDICINE 25: Molecular Imaging Juri Gerlovani 26: Molecular Diagnostics in Cancer Bryan T. Hennessy, Robert C. Bast, Jr., Gordon B. Mills 27: Personalized Medicine in Oncology Drug Development William N. Hait, Nicolas Dracopoli, Steve Heller, Chris H. Takimoto 28: Genomic and Systems Biology Joseph W. Gray 29: Cancer Nanotechnology Mauro Ferrari SECTION 5: CANCER EPIDEMIOLOGY, PREVENTION and SCREENING 30: Cancer Epidemiology Michael J. Thun 31: Prevention of Tobacco-Related Products Steve Hecht, Dorothy Hatsukami 32: Nutrition in the Etiology and Prevention of Cancer Steven K. Clinton 33: Chemoprevention of Cancer Scott M. Lippman, Waun Ki Hong 34: Cancer Screening and Early Detection Robert A. Smith, Stephen W. Duffy, Otis W. Brawley SECTION 6: CLINICAL TRIALS AND OUTCOMES ASSESSMENT 35: Statistical Innovations in Cancer Research Don Berry 36: Outcomes Assessment James A. Talcott PART III: PRINCIPLES OF CANCER DIAGNOSIS SECTION 7: CANCER PATHOLOGY 37: Principles of Cancer Pathology Stan Hamilton SECTION 8: IMAGING 38: Principles of Imaging Edward F. Patz, Jr. 39: Interventional Radiology for the Cancer Patient Michael Wallace, Rony Avritscher PART IV: PRINCIPLES OF THERAPEUTIC MODALITIES SECTION 9: SURGICAL ONCOLOGY 40: Principles of Surgical Oncology Raphael E. Pollock, Michael A. Choti, Donald L. Morton SECTION 10: RADIATION ONCOLOGY 41: Principles of Radiation Oncology Joseph K. Salama, Mark W. Dewhirst, Ralph R. Weichselbaum SECTION 11: MEDICAL ONCOLOGY 42: Principles of Medical Oncology William N. Hait, MD, ,PhD James F. Holland, MD, ScD (hc) Emil Frei III, MD Donald W. Kufe, MD Robert C. Bast Jr, MD Waun Ki Hong, MD SECTION 12: CHEMOTHERAPY 43: Cytokinetics Larry Norton, Theresa Ann Gilewski 44: Principles of Dose, Schedule, and Combination Chemotherapy Joseph P. Eder, William Hait 45: Preclinical and Early Clinical Development of New Anticancer Agents Daniel D. Von Hoff, Axel Hanuske 46: Pharmacology William Plunkett, Mark Ratain 47: Drug Resistance and Its Clinical Circumvention Jeffrey Moscow, Erasmus Schneider, Branimir I. Sikic, Charles S. Morrow, Kenneth H. Cowan SECTION 13: CHEMOTHERAPEUTIC AGENTS 48: Folate Antagonists Joseph R. Bertino, Barton A. Kamen, Peter D. Cole 49: Pyrimidine and Purine Antimetabolites Giuseppe Pizzorno, Sunil Sharma, Yung-Chi Cheng 50: Alkylating Agents and Platinum Antitumor Compounds Michael Colvin 51: Drugs that Target DNA Topoisomerases William N. Hait, Eric H. Rubin 52: Microtubule-Targeting Natural Products Eric Rowinsky SECTION 14: BIOTHERAPEUTICS 53: InterferonsErnest C. Borden 54: Cytokines and Hematopoietic Growth FactorsSuhendan Ekmekcioglu, Razelle Kurzrock, Elizabeth A. Grimm 55: Monoclonal Serotherapy Robert C. Bast, Michael R. Zalutskym, Arthur E. Frankel, Robert J. Kreitman 56: Vaccines and Immunostimulants Jeff Schlom, James L. Gulley, Philip M. Arlen, James W. Hodge SECTION 15: ENDOCRINE THERAPY 57: Estrogens, Antiestrogens and Aromatase Inhibitors Aman U. Buzdar, Shaheenah Dawood, Harold A. Harvey, V. Craig Jordan 58: Androgen Deprivation Strategies In The Treatment Of Advanced Prostate Cancer Samuel R. Denmeade SECTION 16: GENE THERAPY 59: Cancer Gene Therapy Sunil J. Advani, Ralph R. Weichselbaum, Donald W. Kufe SECTION 17: BONE MARROW TRANSPLANTATION 60: Hematopoietic Cell Transplantation Roy Jones, Elizabeth Shpall, Richard Champlin PART V: PRINCIPLES OF MULTIDISCIPLINARY MANAGEMENT SECTION 18: PSYCHO-ONCOLOGY 61: Principles of Psycho-Oncology Jimmie C. Holland SECTION 19: CANCER REHABILITATION MEDICINE 62: Principles of Cancer Rehabilitation Medicine Kristjan T. Ragnarsson SECTION 20: MULTIDISCIPLINARY MANAGEMENT 63: Multidisciplinary Management James F. Holland, Emil Frei III, III, Waun Ki Hong, Donald W. Kufe, Robert C. Bast Jr, Raphael E. Pollock, Ralph R. Weichselbaum, William N. Hait 64: Pregnancy and Cancer Jennifer K. Litton 65: Cancer and Aging Arti Hurria, Hyman B. Muss, Harvey J. Cohen 66: The Role of Integrative Oncology in Cancer Care Lorenzo Cohen, Nancy Russell, Kay Garcia, Moshe Frenkel SECTION 21: PAIN AND PALLIATION 67: Palliative Care Diane Meier, Cardinale B. Smith, Gabrielle R. Goldberg 68: Management of Cancer Pain Natalie Moryl, Alan Carver SECTION 22: CENTRAL NERVOUS SYSTEM 69: Primary Neoplasms of the Central Nervous System in Adults Lisa M. DeAngelis 70: Brain Metastases Lisa M. DeAngelis SECTION 23: THE EYE 71: Neoplasms of the Eye Amy C. Schefler, David H. Abramsom, Ira J. Dunkel, Beryl McCormick SECTION 24: ENDOCRINE GLANDS 72: Neoplasms of the Endocrine Glands: Pituitary Neoplasms Kalman D. Post 73: Neoplasms of the Thyroid Steven I. Sherman 74: Neoplasms of the Adrenal Cortex David E. Schteingart 75: Neuroendocrine System and Gastroentero-pancreatic Endocrine System Evan Vosburgh SECTION 25: HEAD AND NECK 76: Neoplasms of the Head and Neck Michael E. Kupferman, Erich M. Sturgis, David L. Schwartz, Adam Garden, Merrill S. Kies SECTION 26: THE THORAX 77: Cancer of the Lung Charles Lu, Amir Onn, Ara A. Vaporciyan, Joe Y. Chang, Bonnie S. Glisson, Ritsuko Komaki, Ignacio I. Wistuba, Jack A. Roth, Roy S. Herbst 78: Malignant Mesothelioma Harvey I. Pass, Michele Carbone, Hedy Kindler 79: Thymomas and Thymic Tumors A. Philippe Chahinian 80: Tumors of the Heart and Great Vessels Sarina van der Zee, A. Philippe Chahinian, Valentin Fuster 81: Primary Germ Cell Tumors of the Thorax Anthony F. Greco, John D. Hainsworth SECTION 27: GASTROINTESTINAL TRACT 82: Neoplasms of the Esophagus Stephen G. Swisher, David C. Rice, Jaffer A. Ajani, Ritsuko K. Komaki, Mark K. Ferguson 83: Carcinoma of the Stomach Paul Mansfield, James Yao, Christopher Crane, Takeshi Sano 84A: Treatment of Liver Metastases Nancy E. Kemeny, Micheal D'Angelica 84B: Kemeny Treatment of Liver Metastases Max W. Sung, Swan N. Thung 85: Gallbladder and Bile Duct Cancer Ahmed O. Kaseb, Steven A. Curley, Melanie Thomas 86: Neoplasms of the Exocrine Pancreas Robert A. Wolff, Christopher H. Crane, Donghui Li, Douglas B. Evans 87: Neoplasms of the Small Intestine, Vermiform Appendix, Peritoneum and Carcinoma of the Colon and Rectum James C. Padussis, Georgia M. Beasley, Nicole McMahon, Douglas S. Tyler, Kirk Ludwig 88: Neoplasms of the Anus Bruce Minsky SECTION 28: GENITOURINARY TRACT 89: Renal Cell Carcinoma Derek Raghavan, Brian I. Rini, Daniel Y.C. Heng, Ming Zhou, Andrew Novick 90: Tumors Of The Renal Pelvis And Ureter Derek Raghavan, Ali-Reza Golshayan, Inderbir Gill, Cristina Magi-Galluzzi 91: Bladder Cancer Derek Raghavan,John Stein, Richard Cote, J. Stephen Jones 92: Neoplasms of the Prostate Christopher Logothetis 93: Tumors of the Penis and Urethra Donald F. Lynch 94: Testis Cancer Christian Kollmansberger, Siamak Daneshmand, Eric Hansen, Christopher L. Corless, Bruce J. Roth, Craig R. Nichols SECTION 29: FEMALE REPRODUCTIVE ORGANS 95: Neoplasms of the Vulva and Vagina Jacob Rotmensch 96: Neoplasms of the Cervix Anuja Jhingran 97: Endometrial Cancer Carmel J. Cohen, Jamal Rahaman 98: Neoplasms of the Fallopian Tube Carmel J. Cohen, Jamal Rahaman 99: Ovarian Cancer Jonathan S. Berek, Robert Bast, Michael L. Friedlander 100: Molar Pregnancy and Gestational Trophoblastic Neoplasia Ross S. Berkowitz, Dona ld Goldstein 101: Gynecologic Sarcomas Carmel J. Cohen, Jamal Rahaman SECTION 30: THE BREAST 102: Neoplasms of the Breast Gabriel N. Hortobagyi, Laura Esserman, Thomas A. Buchholz SECTION 31: THE SKIN 103: Melanoma Patrick Hwu, Jeff Gershenwald, Boris Bastian 104: Other Skin Cancers Arthur Sober, Victor A. Neel SECTION 32: BONE AND SOFT TISSUE 105: Bone Tumors Tim Damron 106: Soft Tissue Sarcomas Peter Pisters , Brian O'Sullivan, Robert G. Maki SECTION 33: HEMATOPOIETIC SYSTEM 107: The Myelodyplastic Syndrome Lewis R. Silverman 108: Acute Myeloid Leukemia and Other Mast Cell Neoplasms Charles A. Schiffer, Richard M. Stone 109: Chronic Myeloid Leukemia Magop M. Kantarjian, Jorge Cortes 110: Acute Lymphocytic Leukemia Stefan Faderl, Ching-Hon Pui, Susan O'Brien, Hagop M. Kantarjian 111: Chronic Lymphocytic Leukemia Kanti Rai, Matthew Kaufman 112: Hodgkin Disease James O'Armitage, Peter M. Mauch, Lawrence Weiss 113: Non-Hodgkin Lymphoma Arnold S. Freedman 114: Mycosis Fungoides and the Sezary Syndrome Richard T. Hoppe, Youn H. Kim, Ranjana Advani 115: Plasma Cell Tumors Kenneth C. Anderson, Teru Hideshima, Noopur Raje 116: Myeloproliferative Neoplasms: Essential Thrombocythemia, Primary Myelofibrosis and Polycythemia Vera Ayalew Tefferi SECTION 34: NEOPLASMS IN AIDS 117: Neoplasms in Acquired Immunodeficiency Syndrome David T. Scadden, Jeremy S. Abramson SECTION 35: UNKNOWN PRIMARY SITE 118: Neoplasms of Unknown Primary Site John D. Hainsworth, F. Anthony Greco SECTION 36: PEDIATRIC ONCOLOGY 119: Principles of Pediatric Oncology Maura O'Leary, Greg Reaman SECTION 37: COMPLICATIONS OF CANCER AND THEIR TREATMENT 120: Cancer Anorexia and Cachexia Takao Ohnuma 121: Antiemetic Therapy David Ettinger, Aditya Bardia 122: Neurologic Complications Lisa M. DeAngelis 123: Dermatologic Complications of Cancer Chemotherapy Cindy Berthelot, Joy H. Kunishige, Narin Apisarnthanarax, Madeleine M. Duvic 124: Skeletal Complications Samuel Kenan, Jeff Mechanick, Michael Via 125: Hematologic Complications and Blood Bank Support Kenneth C. Anderson, Richard M. Kaufman 126: Coagulopathic Complications of Cancer Patients Jacob H. Rand, Maria DeSancho 127: Urologic Complications Christopher J. Logothetis, Diana M. Hey 128: Cardiac Complications Michael S. Ewer, Steven M. Ewer, Thomas Suter 129: Respiratory Complications Vickie R. Shannon, George A. Eapen, Carlos A. Jimenez, Rodolfo C. Morice, Elizabeth L. Travis, Lara Bashoura, Amar Safdar, Scott E. Evans, Roberto Adachi, Saadia A. Faiz, Diwakar D. Balachandran, Joseph L. Nates, S. Egbert Pravinkumar, Burton F. Dickey 130: Gastrointestinal and Hepatic Complications in Cancer Patients Robert Bresalier, Marta L. Davila 131: Oral Complications of Cancer and Their Treatment Stephen T. Sonis 132: Gonadal Complications Catherine E. Klein, Peter Kabos 133: Endocrine Complications and Paraneoplastic Syndromes Robert F. Gagel, Sai-Ching, Jim Yeung 134: Treatment -Related Secondary Cancers Susan R. Rheingold, Alfred I. Neugut, Thomas Uldrick, Anna T. Meadows SECTION 38: INFECTION IN THE CANCER PATIENT 135: Infections in Patients with Cancer Kenneth V.I. Rolston, Gerald P. Bodey SECTION 39: ONCOLOGIC EMERGENCIES 136: Oncologic Emergencies S. Jim Yeung, Carmen Escalante SECTION 40: ONCOLOGY AND INFORMATICS 137: Oncology Informatics Edward P. Ambinder
| Erscheint lt. Verlag | 16.2.2010 |
|---|---|
| Zusatzinfo | illustrations |
| Verlagsort | Shelton |
| Sprache | englisch |
| Maße | 216 x 286 mm |
| Gewicht | 4553 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| ISBN-10 | 1-60795-014-6 / 1607950146 |
| ISBN-13 | 978-1-60795-014-1 / 9781607950141 |
| Zustand | Neuware |
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