Fluorine in Heterocyclic Chemistry Volume 1 (eBook)
IX, 681 Seiten
Springer International Publishing (Verlag)
978-3-319-04346-3 (ISBN)
This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.
Valentine G. Nenajdenko was born in 1967 in Ivanovo, Russia. He graduated from Moscow State University (Lomonosov) in 1991. He received his Ph.D. degree under the supervision of Professor E.S. Balenkova in 1994 researching the synthesis and application of unsaturated CF3 ketones. In 2000 he received Dr. of Chemistry degree involving the chemistry of sulfonium and iminium salts. In 2003 he became full Professor of Organic Chemistry at the Department of Chemistry of Moscow State University. His scientific interests include organic synthesis, asymmetric catalysis, the chemistry of sulfur and fluorine containing compounds, heterocyclic chemistry, multicomponent reactions. He have been a supervisor of 12 postgraduate studies. Prof. Nenajdenko is head of the Scientific Committee and Jury of International Mendeleev Chemistry Olympiad. He was the winner of the Academiae Europeae Award in 1997, the Russian President Award in 1996, the Prize for the best scientific work at the Department of Chemistry of Moscow State University in 2001 and 2007, the Shuvalov Award in 2001, the Russian President Award in 2004, Russian Science Support Foundation in 2005, Moscow State University Awards in 2006, 2007 and 2008.
Valentine G. Nenajdenko was born in 1967 in Ivanovo, Russia. He graduated from Moscow State University (Lomonosov) in 1991. He received his Ph.D. degree under the supervision of Professor E.S. Balenkova in 1994 researching the synthesis and application of unsaturated CF3 ketones. In 2000 he received Dr. of Chemistry degree involving the chemistry of sulfonium and iminium salts. In 2003 he became full Professor of Organic Chemistry at the Department of Chemistry of Moscow State University. His scientific interests include organic synthesis, asymmetric catalysis, the chemistry of sulfur and fluorine containing compounds, heterocyclic chemistry, multicomponent reactions. He have been a supervisor of 12 postgraduate studies. Prof. Nenajdenko is head of the Scientific Committee and Jury of International Mendeleev Chemistry Olympiad. He was the winner of the Academiae Europeae Award in 1997, the Russian President Award in 1996, the Prize for the best scientific work at the Department of Chemistry of Moscow State University in 2001 and 2007, the Shuvalov Award in 2001, the Russian President Award in 2004, Russian Science Support Foundation in 2005, Moscow State University Awards in 2006, 2007 and 2008.
Tactical Applications of Fluorine in Drug Design and Development Kyle; J. Eastman et al.- Chemistry of Fluorinated Pyrroles; V. M. Muzalevskiy et al.- Chemistry of Fluorinated Indoles; O. V. Serdyuk et al.- Fluorinated Indolizines, E.V. Babaev.- Fluorinated Furans and Benzofurans; I. V. Trushkov et al.- Fluorinated Thiophenes and their Analogues; O. V. Serdyuk et al.- Fluorinated Pyrazoles and Indazoles; S. Fustero et al.- Fluorinated Imidazoles and Benzimidazoles; S. Roy et al.- Fluorinated Oxazoles, Thiazoles and Selenazoles; M.A. Yurovskaya.- Chemistry of Fluorinated Oxadiazoles and Thiadiazoles; A. Pace,* A. Palumbo Piccionello et al.- Fluorinated Triazoles and Tetrazoles; V. A. Ostrovskii, R. E. Trifonov.- 1,2-Bis (hetaryl) Perfluorocyclopentenes as Unique Thermally Irreversible Photochromes. Synthesis and Structural Singularities; M.M. Krayushkin, M.A.Kalik.- Chemistry of α-Fluorinated Ethers- and Thioethers- Containing Heterocycles; O. Kazakova et al.- Fluorinated Porphyrins and Corroles: Synthesis, Electrochemistry, and Applications; J.C. Biffinger et al.- Fluorinated Phthalocyanines and their Analogues; P.A. Stuzhin.
Erscheint lt. Verlag | 30.6.2014 |
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Zusatzinfo | IX, 681 p. 1205 illus., 17 illus. in color. |
Verlagsort | Cham |
Sprache | englisch |
Themenwelt | Medizin / Pharmazie |
Naturwissenschaften ► Chemie ► Organische Chemie | |
Technik ► Maschinenbau | |
Schlagworte | 5-Membered Rings with Fluorine Substitutions • Alkyl-Halides in Heterocyclic Synthesis • Drug Design with Fluorine • Fluorinated Biomaterials • Fluorinated Heterocyclic Chemistry • Fluorine in Heterocyclic Chemistry • Physiochemical Properties of Fluorinated Heterocyclic Compounds • SN2 Reactions with Fluorine • Synthetic Fluorochemistry |
ISBN-10 | 3-319-04346-3 / 3319043463 |
ISBN-13 | 978-3-319-04346-3 / 9783319043463 |
Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
Haben Sie eine Frage zum Produkt? |

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