Veterinary Epidemiology

MICHAEL THRUSFIELD is Professor of Veterinary Epidemiology at the Royal (Dick) School of Veterinary Studies in the University of Edinburgh in Edinburgh, UK.

ROBERT CHRISTLEY is Professor of Epidemiology and One Health at the Institute of Infection and Global Health and the Institute of Veterinary Science in the University of Liverpool in Liverpool, UK.

Contributors


From the preface to the first edition


From the preface to the second edition


From the preface to the third edition


Preface to the fourth edition


About the companion website


1 The development of veterinary medicine
Michael Thrusfield


2 The scope of epidemiology
Michael Thrusfield


3 Causality
Michael Thrusfield


4 Describing disease occurrence
Michael Thrusfield


5 Determinants of disease
Michael Thrusfield


6 The transmission and maintenance of infection
Michael Thrusfield


7 The ecology of disease
Michael Thrusfield


8 Patterns of disease
Michael Thrusfield


9 Comparative epidemiology
Michael Thrusfield


10 The nature of data
Michael Thrusfield


11 Data collection and management
Michael Thrusfield


12 Presenting numerical data
Michael Thrusfield and Robert Christley


13 Surveys
Michael Thrusfield and Helen Brown


14 Demonstrating association
Michael Thrusfield


15 Observational studies
Michael Thrusfield


16 Design considerations for observational studies
Robert Christley and Nigel French


17 Clinical trials
Michael Thrusfield


18 Validity in epidemiological studies
Robert Christley and Nigel French


19 Systematic reviews
Annette O Connor, Jan Sargeant and Hannah Wood


20 Diagnostic testing
Michael Thrusfield


21 Surveillance
Michael Thrusfield


22 Statistical modelling
Robert Christley and Peter J. Diggle


23 Mathematical modelling
Michael Thrusfield


24 Risk analysis
Michael Thrusfield and Louise Kelly


25 Economics and veterinary epidemiology
Keith Howe and Michael Thrusfield


26 Health schemes
Michael Thrusfield


27 The control and eradication of disease
Michael Thrusfield


Appendix I: Glossary of terms


Appendix II: Basic mathematical notation and terms


Appendix III: Some computer software


Appendix IV: Veterinary epidemiology on the Internet


Appendix V: Student s t-distribution


Appendix VI: Multipliers used in the construction of confidence intervals based on the Normal distribution, for selected levels of confidence


Appendix VII: Values of exact 95% confidence limits for proportions


Appendix VIII: Values from the Poisson distribution for calculating 90%, 95% and 99% confidence intervals for observed numbers from 0 to 100


Appendix IX: The 2 distribution


Appendix X: Technique for selecting a simple random sample


Appendix XI: Sample sizes


Appendix XII: The probability of detecting a small number of cases in a population


Appendix XIII: The probability of failure to detect cases in a population


Appendix XIV: Sample sizes required for detecting disease with probability, p1, and threshold number of positives


Appendix XV: Probabilities associated with the upper tail of the Normal distribution


Appendix XVI: Lower- and upper-tail probabilities for Wx, the Wilcoxon Mann Whitney rank-sum statistic


Appendix XVII: Critical values of T + for the Wilcoxon signed ranks test


Appendix XVIII: Values of K for calculating 95% confidence intervals for the difference between population medians for two independent samples


Appendix XIX: Values of K for calculating 95% confidence intervals for the difference between population medians for two related samples


Appendix XX: Common logarithms (log10) of factorials of the integers 1 999


Appendix XXI: The correlation coefficient


Appendix XXII: The variance-ratio (F) distribution


References


Index