Comparative Pharmacokinetics – Principles, Techniques and Applications 3e - JE Riviere

Comparative Pharmacokinetics – Principles, Techniques and Applications 3e

JE Riviere (Autor)

Software / Digital Media
376 Seiten
2011
Wiley-Blackwell (Hersteller)
978-0-470-95991-6 (ISBN)
163,63 inkl. MwSt
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Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner. Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book provides complete coverage of the conceptual basis of pharmacokinetics as used for quantifying biological processes from the perspectives of physiology and medicine. New chapters have been added on quantitative structure permeability relationships and bioequivalence, and a number of existing chapters have been significantly revised and expanded to provide a current resource for veterinary and comparative pharmacokinetics.

Jim E. Riviere , D.V.M., Ph.D. is the Burroughs Wellcome Fund Distinguished Professor of Veterinary Pharmacology and Director, Center for Chemical Toxicology Research and Pharmacokinetics, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, N.C. .

Introduction; Principles of drug movement in the body; Absorption; Distribution; Renal Elimination; Hepatic biotransformation and biliary excretion; Compartmental models; Noncompartmental models; Nonlinear models; Physiological models; Dosage regimens; Simultaneous pharmacokinetics-pharmacodynamics modeling; Study design and data analysis; Population pharmacokinetics models and Bayesian forecasting applied to clinical pharmacokinetics; Dosage adjustment in renal diseases; Interspecies extrapolations; Tissue residues and withdrawal times, Index.

Verlagsort Hoboken
Sprache englisch
Maße 150 x 250 mm
Gewicht 666 g
Themenwelt Veterinärmedizin
ISBN-10 0-470-95991-6 / 0470959916
ISBN-13 978-0-470-95991-6 / 9780470959916
Zustand Neuware
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