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Human Toxicology of Chemical Mixtures

Toxic Consequences Beyond the Impact of One-Component Product and Environmental Exposures

(Autor)

Buch | Hardcover
400 Seiten
2008
William Andrew Publishing (Verlag)
978-0-8155-1589-0 (ISBN)
218,20 inkl. MwSt
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Considers how exposure to toxic mixtures affects the different physiological systems and organs, including the respiratory, cardiovascular, immunological, musculoskeletal, nervous and reproductive systems, as well as the various organs, including the kidneys, liver and skin.
This book considers how exposure to toxic mixtures affects the different physiological systems and organs, including the respiratory, cardiovascular, immunological, musculoskeletal, nervous and reproductive systems, as well as the various organs, including the kidneys, liver and skin.The author evaluates various sources of exposure, including air, water, and soil pollution; in utero exposure; chemicals contained in foods, cosmetics, and domestic cleaning products; adhesives and paints; industrial chemicals; pesticides; electromagnetic radiation; and chemicals ingested or inhaled during the use of alcohol, tobacco and narcotics.The book also examines the interplay between exposure to these mixtures and the prevalence of various diseases and conditions, including autism, attention deficit hyperactivity disorder (ADHD), developmental neurotoxicology, multiple chemical sensitivity (MSC), chronic fatigue syndrome (CFS), fibromyalgia (FM), Gulf war syndrome, cancer and cancer clusters. The author also discusses how exposure to these mixtures yields the above diseases and conditions in different populations: fetuses, infants, pre-adolescent children, adolescents and adults.Finally, the book addresses the profound policy implications for formulation, labeling and use of chemical products, and it proposes more stringent exposure limits and warning requirements in light of the newly recognized toxic effects that are directly attributable to the mixture of toxic lipophilic and hydrophilic chemicals.

Dr. Harold I. Zeliger holds a PhD in organic chemistry and has been a professor of chemistry and environmental science. He is a Certified Professional Chemist, a Board- Certified Forensic Examiner, and an EPA Certified Laboratory Director. Dr. Zeliger is the author of 51 technical publications, including basic research journal articles and patents. In his more than 40 years in the Chemical Process Industry, he has personally developed many industrial and consumer chemical products, designed chemical product warning labels and written Material Safety Data Sheets for toxic and flammable chemicals. Dr. Zeliger has investigated hundreds of toxic chemical exposures, environmental spills and discharges, chemical fires and explosions nationally and internationally. He has served repeatedly as an expert witness for both plaintiffs and defendants in chemical product, process, toxic exposure, environmental, flammable, intellectual property and subrogation claims. Dr. Zeliger has provided services for numerous forensic examinations, technology transfer and due diligence investigations. Dr. Zeliger’s research is in the area of chemical toxicology. His published work includes papers on the toxic effects of chemical mixtures and chemical causes of cancer clusters and two editions of Human Toxicology of Chemical Mixtures, Second Edition.

PART I Introduction to Chemical Toxicology of MixturesIntroductionHealth Effects of Exposures to Chemical MixturesAbsorption of Chemical MixturesChemical ToxicologyPART II Exposures to Chemical MixturesScope and sources of toxic exposuresIn Utero ExposureAir PollutionWater PollutionSoil PollutionFoodChemicals In and Around The HomeSick Building SyndromeIndustrial ExposurePesticidesAlcohol and Tobacco: Recreational ToxinsElectromagnetic Radiation and Toxic ExposurePART III Mixture Effects on Body SystemsRespiratory SystemNervous SystemDevelopmental NeurotoxicologyAutism: Effect of Maternal Exposure to Neurotoxic ChemcialsAttention Deficit Hyperactivity Disorder (ADHD)Endocrine SystemToxic InfertilityTeratogensImmune SystemChemical Sensitivity: Multiple Chemical Sensitivity (MCS)SkinMusculoskeletal SystemCardiovascular SystemLiverKidneysCancerChildhood CancerCancer ClustersPART IV REGULATORY REQUIREMENTS, CONCLUSIONSRegulatory RequirementsConclusions

Erscheint lt. Verlag 25.7.2008
Verlagsort Norwich
Sprache englisch
Maße 152 x 229 mm
Gewicht 940 g
Themenwelt Medizin / Pharmazie Pharmazie
Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
Technik
ISBN-10 0-8155-1589-8 / 0815515898
ISBN-13 978-0-8155-1589-0 / 9780815515890
Zustand Neuware
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