Pharmaceutical Dosage Forms - Tablets

LARRY L. AUGSBURGER is Professor Emeritus, University of Maryland School of Pharmacy, Baltimore, and a member of the Scientific Advisory Committee, International Pharmaceutical Excipients Council of the Americas (IPEC). Dr. Augsburger received his Ph.D. in Pharmaceutical Science from the University of Maryland, Baltimore. The focus of his research covers the design and optimization of immediate release and extended release oral solid dosage forms, the instrumentation of automatic capsule filling machines, tablet presses and other pharmaceutical processing equipment, and the product quality and performance of nutraceuticals (dietary supplements). Dr. Augsburger has also published over 115 papers and three books, including Pharmaceutical Excipients Towards the 21st Century published by Informa Healthcare. STEPHEN W. HOAG is Associate Professor, School of Pharmacy, University of Maryland, Baltimore. Dr. Hoag received his Ph.D. in Pharmaceutical Science from the University of Minnesota, Minneapolis. The focus of his research covers Tablet Formulation and Material, Characterization, Process Analytical Technology (PAT), Near Infrared (NIR) Analysis of Solid Oral Dosage Forms, Controlled Release Polymer Characterization, Powder Flow, Thermal Analysis of Polymers, Mass Transfer and Controlled Release Gels. Dr. Hoag has also published over 40 papers, has licensed four patents, and has written more than five books, including Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, Third Edition and Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems, both published by Informa Healthcare.

Preface. Tooling for Pharmaceutical Processing. Tablet Press Instrumentation in the Research and Development Environment. Pharmaceutical Manufacturing: Changes in Paradigms. A Forward-Looking Approach to Process Scale-Up for Solid Dose Manufacturing. Dissolution and Drug Release. Setting Dissolution Specifications. Mechanical Strength of Tablets. CGMPs for the 21st Century and ICH Quality Initiatives. Intellectual Property, Patent and Patenting Process in Pharmaceutical Industry. Near-Infrared Chemical Imaging of Pharmaceutical Oral Solid Dosage Forms. Surface Area, Porosity and Related Physical Characteristics.