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Oral Delivery of Insulin

T.A. Sonia, Chandra P. Sharma (Autoren)

Buch | Hardcover

400 Seiten

2025 | 2nd edition
Woodhead Publishing (Verlag)
978-0-443-30272-5 (ISBN)

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Oral delivery of Insulin, Second Edition is a complete reference on non-invasive insulin delivery systems, focusing on the prospect of oral delivery of peptides. The chapters in the revised edition present a comprehensive evaluation of the insulin therapy approaches with emphasis on insulin delivery strategies and current advances in engineered insulin delivery systems such as nano/microcarriers, and hydrogels. Including two new chapters, the contents were substantially updated. The first chapter provides an overview of diabetes mellitus, the second chapters covers the technological innovations in the treatment of diabetes, including pancreatic islet cell transplantation, stem cell therapy, β-cells regeneration and gene therapy incretin therapy, statin therapy, metabolic surgery, and precision medicine approaches. Chapter three covers artificial intelligence and machine learning approaches to manage diabetes, including regulatory aspects. Chapter four explores a wide range of non-invasive and alternative routes of insulin administration. Chapter five covers the challenges and strategies in oral insulin delivery. Chapter six covers the experimental techniques used to develop oral insulin carriers. The next chapter is focused on the use of polymeric nano and microparticles for insulin delivery. Chapter eight focus on the use of lipids and inorganic nanoparticles in insulin delivery. The final chapter provide an overview of current clinical trials on insulin delivery and future perspectives in the area. Oral delivery of Insulin, Second Edition provides an updated and comprehensive overview of the current developments in non-invasive insulin delivery strategies. Pharmaceutical scientists will benefit from the broad coverage. Biomedical engineers can better understand combination approaches to develop new devices. Clinicians can benefit from this information to develop a clear understanding about the research carried out worldwide in the field of oral delivery of insulin including those in the clinical phase.

Sonia T.A pursued her PhD under the guidance of Dr Chandra P Sharma at the Biosurface Technology Division, Sree Chitra Tirunal Institute for Medical Science & Technology in Kerala, India. She worked in the field of development of polymeric nano/micro particles for oral delivery of insulin. She completed her graduate studies in Polymer science from the School of Chemical Sciences, Mahatma Gandhi University, Kerala India. She has presented her work in International Conferences. Dr. Chandra P. Sharma is Adjunct Professor, Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal University, and Hon. Emeritus Professor, College of Biomedical Engineering & Applied Sciences, Purbanchal University, Kathmandu, Nepal. Dr. Sharma is a Solid-State Physicist from IIT Delhi and received his training in Biomaterials area in the University of Utah with Prof. D.J. Lyman as a graduate student and in the University of Liverpool, England with Prof. D.F. Williams as a Post-Doctoral Research Associate. Dr. Sharma has been awarded FBSE (Fellow Biomaterials Science & Engineering) by The International Union of Societies for Biomaterials Science & Engineering (IUS-BSE) in 2008 and FBAO (Fellow Biomaterials and Artificial Organs) by Society for Biomaterials & Artificial Organs (India) (SBAOI) in 2011 and shares Whitaker and National Science Foundation Award – International Society for Artificial Organs (ISAO) USA, invited member ACS (2015-2018).

1. Diabetes Mellitus – an overview
2. Technological Innovations in the treatment of Diabetes over the last decade
3. Artificial intelligence/Machine Learning in management of Diabetes
4. Alternative/Non-invasive routes of administration of Insulin
5. Oral insulin delivery – Challenges and strategies
6. Experimental Techniques involved in the development of orally administered insulin carrier.
7. Polymeric Nano/microparticles for oral insulin delivery
8. Lipids and Inorganic nanoparticles in oral insulin delivery
9. Clinical trials on insulin delivery and future perspectives

Erscheint lt. Verlag	1.6.2025
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Technik
ISBN-10	0-443-30272-3 / 0443302723
ISBN-13	978-0-443-30272-5 / 9780443302725
Zustand	Neuware