Nonlinear Dynamics of Parkinson's Disease and the Basal Ganglia-Thalamic-Cortical System (eBook)

Nonlinear Dynamics of Parkinson's Disease and the Basal Ganglia-Thalamic-Cortical System examines current research regarding the operations of the basal ganglia-thalamic-cortical system that causes neurological disorders like Parkinson's disease. While there have been remarkable advances in the understanding of the anatomy, physiology and chemistry of these systems, there remains a significant degree of inconsistency and incompleteness between facts and advancements. This book introduces the novel concepts of nonlinear complex systems and their connection to Parkinsonism as well as hyperkinetic disorders. The actual mechanisms underlying the motor disorders of Parkinson's disease at the level of the lower motor neuron are also discussed. - Outlines phenomenological selectivity of pallidotomy and Deep Brain Stimulation - Reviews the anatomical models of pathophysiology and physiology - Discusses the instrumental and analytical misrepresentations and the inferences that misrepresent the data in Nonmonotonic Nonlinear Dynamics

Dr. Montgomery has been an academic neurologist for over 40 years pursuing teaching, clinical and basic research at major academic medical centers. He has authored over 120 peer reviewed journal articles (available on PubMed) and 8 books on medicine (4 on the subject of Deep Brain Stimulation). The last two have been 'Reproducibility in Biomedical Research” (Academic Press, 2024) and 'The Ethics of Everyday Medicine” (Academic Press, 2023).

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Nonlinear Dynamics of Parkinson's Disease and the Basal Ganglia-Thalamic-Cortical System examines current research regarding the operations of the basal ganglia-thalamic-cortical system that causes neurological disorders like Parkinson's disease. While there have been remarkable advances in the understanding of the anatomy, physiology and chemistry of these systems, there remains a significant degree of inconsistency and incompleteness between facts and advancements. This book introduces the novel concepts of nonlinear complex systems and their connection to Parkinsonism as well as hyperkinetic disorders. The actual mechanisms underlying the motor disorders of Parkinson's disease at the level of the lower motor neuron are also discussed. - Outlines phenomenological selectivity of pallidotomy and Deep Brain Stimulation- Reviews the anatomical models of pathophysiology and physiology- Discusses the instrumental and analytical misrepresentations and the inferences that misrepresent the data in Nonmonotonic Nonlinear Dynamics