Personalized Medicine Meets Artificial Intelligence

Alfredo Cesario Open Innovation Manager at the Fondazione Policlinico Universitario A. Gemelli IRCCS (Rome, Italy, www.policlinicogemelli.it). CEO, Gemelli Digital Medicine and Health Srl (GDMH, www.gdmh.it). Marika D'Oria PhD in Education and Communication. Health Communication Officer for the Scientific Directorate (Open Innovation Unit) at the Fondazione Policlinico Universitario A. Gemelli IRCCS (Rome, Italy).  Charles Auffray Founding Director at the European Institute for Systems Biology and Medicine (Lyon, France) and CNRS Research Director at the Joliot Curie Transdisciplinary Laboratory and École Normale Supérieure (Lyon, France). Giovanni Scambia Scientific Director at the Fondazione Policlinico Universitario A. Gemelli IRCCS and Full Professor in “Gynecology and Obstetrics” at the Catholic University of the Sacred Heart (Rome, Italy).

Part I. State of the Art.- Chapter 1. Personalized Medicine Through Artificial Intelligence: A Public Health Perspective.- Chapter 2. Artificial Intelligence and Digital Health: An International Biomedical Perspective.- Chapter 3. GDPR as a First Step Towards Free Flow of Data in Europe.- Chapter 4. Digital Therapeutics: Scientific, Technological, and Regulatory Challenges.- Chapter 5. Intelligence-Based Medicine: The Academic Perspective and Deep Humanism.- Part II. Consolidated Evidence.- Chapter 6. The Role of Big Data and Artificial Intelligence in Clinical Research and Digital Therapeutics.- Chapter 7. Systems Pharmacology for Immunotherapy: A Network Analysis of Signaling Pathways in Multiple Sclerosis for Combination Therapy Development.- Chapter 8. Approaches to Generating Virtual Patient Cohorts with Applications in Oncology.- Chapter 9. Artificial Intelligence and Deep Phenotyping in COVID-19.- Chapter 10. Multilevel Modelling with AI: The Synergy-COPD Endeavour.- Chapter 11. Artificial Intelligence and Radiotherapy: Impact on Radiotherapy Workflow and Clinical Example.- Chapter 12. Artificial Intelligence in Surgery.- Part III. Emerging and Future Technologies.- Chapter 13. How Start-ups and Established Organisations Together Can Drive Meaningful Healthcare Innovation in Personalised Medicine and AI.- Chapter 14. Artificial Intelligence Augmented Medtech: Towards Personalized Patient Treatment.- Chapter 15. Quantum Computing: Promises and Challenges.- Chapter 16. Metaverse Means Better: How the Metaverse Continuum Is Evolving Healthcare to the Next Level.- Chapter 17. Patients' Reactions to Anthropomorphic Technologies in Healthcare. The Predictor Roles of Perceived Anthropomorphism and Human-Like Interaction: A Preliminarily Study.- Chapter 18. Some Ethical and Educational Perspectives on Using Artificial Intelligence in Personalized Medicine and Healthcare.- Chapter 19. The "Human Factor" Beyond Humans: Perspectives for an AI-Guided Personalized Medicine.