Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics

Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist. Dr. Kalyan Kumar Sen (MPharm, PhD) has over 38 years of teaching and industrial and research experience in the field of pharmaceutics, especially in the development and characterization of novel drug delivery systems. He has earned his PhD in pharmacy from Jadavpur University, India. Currently, Dr. Sen is working as a principal and professor of Gupta College of Technological Sciences, Asansol, India. Till date, he has authored several publications in various journals of international repute. He has authored several book chapters. He already has edited two books and co-authored one book. He has been the permanent reviewer of many international journals of high repute. Dr. Sen has participated and presented his research work at several conferences in India. Dr. Sen is a life member of the APTI and several professional bodies.

Section I: Physico-chemical aspects of dosage forms 1. Physico-chemical factors influencing drug degradation 2. Stability and accelerated stability studies of dosage forms 3. Solubility of drugs 4. Drug dissolution studies of pharmaceutical formulations 5. Pharmaceutical granulation: Engineering perspective and futuristic trends 6. Tablet compression and consolidation: Theory and applications Section II: Biopharmaceutics 7. Introduction to Biopharmaceutics 8. Gastrointestinal absorption of drugs 9. Routes of drug administration and their impact in biopharmaceutics 10. Drug elimination and renal excretion of drugs 11. Membrane transport and permeation of drugs 12. Factors affecting drug absorption and disposition 13. Bioavailability and bioequivalence 14. Contribution of biopharmaceutics and pharmacokinetics to improve drug therapy 15. Dosage regimen 16. Multicompartment models 17. Nonlinear pharmacokinetics 18. Computer-aided biopharmaceutical model development 19. Computer simulations in pharmacokinetics 20. WHO and ICH Guidelines for ‘Good Manufacturing Practices’ 21. Pilot plant scale up techniques in pharmaceutical product development 22. Advances in solid dosage forms