Microbes and Oral Squamous Cell Carcinoma (eBook)

This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention.

The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like for this area of research.

The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.

Dr. Samapika Routray (MDS, Oral Pathology and Microbiology) is an Assistant Professor at All India Institute of Medical Sciences, Bhubaneswar, in the Department of Dentistry. She completed her post-graduation from Dr D Y Patil Vidyapeeth, Pune, India in 2010. She was awarded distinction for Pedodontics and Preventive Dentistry in her undergraduate. She has previously worked as an Associate Professor, Department of Oral Pathology, Faculty of Dental Sciences, and Bhubaneswar pursuing her dream project in early diagnosis of Oral cancer. She has more than 44 peer reviewed national and international publications including Nature, Elsevier. Springer, Wiley, etc. She has authored 8 book chapters and has attended numerous oral and posters presentations in international meetings. She was selected for Rotary Exchange Program and visited Michigan in 2012. She also did a Short term Fellowship, Institute of Surgical Pathology, University Hospital Zurich (2015).

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This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention.The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like forthis area of research.The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.