The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics: Part B

Marc E. Lavoie, PhD is currently research professor of Psychiatry and Neuroscience at the University of Montréal, and since 2001 he is directing the Cognitive and Social Psychophysiology Laboratory, at the research center of the Institut Universitaire en Santé Mentale de Montréal (Canada). His research training was completed in the field of psychophysics (Université de Moncton, Canada), experimental neuropsychology (Université de Montréal, Canada), developmental psychology (Universiteit van Amsterdam, the Nederland) and in psychobiology (Université de Lille, France). He directs a clinical research program currently funded by the Canadian Institutes of Health Research that addresses crucial issues about the relationship between brain functions, behavior, and cognition in various neurodevelopmental and habit disorders, primarily in Tourette’s syndrome and behavior-focused repetitive behavior. Andrea E. Cavanna, MD, PhD, FRCP, FANPA, SFHEA, works as a clinician (Consultant in Behavioural Neurology at the Department of Neuropsychiatry, National Centre for Mental Health, Birmingham, UK) and as an academic (Honorary Professor in Neuropsychiatry at Aston University, Birmingham, UK). His medical training was completed in Italy (University of Turin and A. Avogadro University, Novara) and in the United Kingdom (University College London). Since 2008 he has been Lead Consultant for the specialist Tourette syndrome clinic. His research activity focuses on the behavioural aspects of neurological conditions. He coordinates training activities directed at the future generation of clinical scientists by running the Tourette syndrome module of the MSc in Clinical Neuropsychiatry at the University of Birmingham.

Preface Marc E. Lavoie and Andrea E. Cavanna 1. The genetic basis of Gilles de la Tourette syndrome Sarah B. Abdallah, Evan Realbuto, Mary Oluwatosin Kaka, Kelly Yang, Apostolia Topaloudi, Peristera Paschou, Jeremiah M. Scharf and Thomas V. Fernandez 2. Studying the pathophysiology of tic disorders in animal models Christopher Pittenger 3. The neural-immune crosstalk in Tourette syndrome: From immunobiology to epistemology Yasamin Mahjoub, Davide Martino and Andrea E. Cavanna 4. Functional connectivity in the Gilles de la Tourette syndrome Matthew Feigelis and Deanna J. Greene 5. Perception-action integration in Gilles de la Tourette syndrome Theresa Paulus, Christian Beste and Alexander Münchau 6. The pharmacological treatment of Tourette syndrome José Fidel Baizabal-Carvallo and Joseph Jankovic 7. Ecopipam: A D1 receptor antagonist for the treatment of Tourette syndrome Richard E. Chipkin, Donald L. Gilbert and Atul Mahableshwarkar 8. Atypical antipsychotics for treatment of Tourette syndrome Vamsi K. Kalari, Peter E. Morrison and Cathy L. Budman 9. Alpha agonists for the treatment of Tourette syndrome Nick Cothros and Tamara Pringsheim 10. Cannabinoids: Possible role in the pathophysiology and therapy of Gilles de la Tourette syndrome Natalia Szejko and Kirsten Müller-Vahl 11. Novel potential avenues for the therapy of Tourette syndrome: Cannabinoid and steroid-based tools Marco Bortolato and Roberto Cadeddu 12. Non-invasive brain stimulation for the treatment of Tourette's syndrome Sneha Chenji, Kayla D. Stone and Frank P. MacMaster 13. Entrainment of movement-related brain oscillations to improve symptoms in Tourette syndrome Mairi Houlgreave, Bàrbara Morera Maiquez, Katherine Dyke, Georgina Jackson and Stephen Jackson 14. Network oscillatory activity in chronic tics and Tourette syndrome Joohi Jimenez-Shahed