Pharmaceutical Powder Compaction Technology

Revised to reflect modern pharmaceutical compacting techniques, this Second Edition explores compaction of powder constituents (both active ingredient and excipients) and guides pharmaceutical engineers, formulation scientists, product development and quality assurance personnel through the compaction formulation process to ensure consistent and

---

Compaction of powder constituents—both active ingredient and excipients—is examined to ensure consistent and reproducible disintegration and dispersion profiles. Revised to reflect modern pharmaceutical compacting techniques, this second edition of Pharmaceutical Powder Compaction Technology guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application.



This unique reference covers:
















The physical structure of pharmaceutical compacts



Bonding phenomena that occur during powder compaction



Compression mechanisms of pharmaceutical particles



Theories and basic principles of powder compaction












New topics include:
















Compaction data analysis techniques



The migration of powder constituents into commercial manufacture



Instrumentation for compaction



Compaction functionality testing, which is likely to become a USP requirement



Design space for compaction



Metrics required for scalability in tablet compression



Interactive compaction and preformulation database for commonly used excipients